Sebastian Wenk

Assistant Professor

University of Groningen

Netherlands

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Sebastian Wenk is an Assistant Professor at the University of Groningen in the Netherlands. His research focuses on synthetic C1 metabolism, particularly in Pseudomonas putida and Escherichia coli, exploring metabolic pathways and engineering strategies for formic acid and methanol utilization. Recent publications include studies on the reductive glycine pathway, biosensor optimization, and the advancement of CO2-based bioeconomy initiatives.

Articles (10)

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2025

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2025

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2025

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2024

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2024

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2023

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2023

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2022

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2020

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2020

Collaborators (4)

Nicole Paczia

Head of Metabolomics

Max-Planck-Institut für terrestrische Mikrobiologie

GERMANY

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Seung Hwan Lee

Assistant Professor

University of Minnesota Twin Cities

UNITED STATES

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Jan Zarzycki

Max-Planck-Institut für terrestrische Mikrobiologie

GERMANY

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Vitor A.P. Martins dos Santos

Professor of Biomanufacturing & Digital Twins

Wageningen University & Research

NETHERLANDS

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Sebastian Wenk

Research Interests

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Articles (10)

Synthetic C1 metabolism in Pseudomonas putida enables strict formatotrophy and methylotrophy via the reductive glycine pathway.

Evolution-assisted engineering of E. coli enables growth on formic acid at ambient CO2 via the Serine Threonine Cycle

Designer-Mikroben für eine CO2-basierte Bioökonomie

Design, construction and optimization of formaldehyde growth biosensors with broad application in biotechnology

The Serine Shunt enables formate conversion to formaldehyde in vivo

Engineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo

Paving the way for synthetic C1 - Metabolism in Pseudomonas putida through the reductive glycine pathway

Synthetic metabolism approaches

An “energy-auxotroph” Escherichia coli provides an in vivo platform for assessing NADH regeneration systems

Growth of E. coli on formate and methanol via the reductive glycine pathway

Collaborators (4)

Nicole Paczia

Seung Hwan Lee

Jan Zarzycki

Vitor A.P. Martins dos Santos

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