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Shireen Lamande

Has grant

Group Leader

Murdoch Childrens Research Institute
Country flagAustralia

Research Interests

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Recent Grants

Grant: Open

Replicating the cartilage micromechanical environment

Open Date: 2024-05-31

Close Date: 2027-05-30

Grant: Close

Rebalancing the proteostasis network with small molecule therapeutics to treat genetic skeletal diseases

Open Date: 2023-12-15

Close Date:

Grant: Close

Making a Niche: an in vitro human bone marrow organoid factory for blood

Open Date: 2021-11-04

Close Date:

Grant: Close

New therapeutic approaches for genetic skeletal disorders

Open Date: 2021-01-01

Close Date: 2023-12-01

Grant: Close

Skeletal Disease in a Dish: Using novel in vitro disease models produced from patient induced pluripotent stem cells to reveal pathogenic mechanisms and explore treatments for genetic skeletal disorders

Open Date: 2018-01-01

Close Date: 2020-01-01

Articles (12)

Year:

2025

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2025

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2025

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2025

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2024

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2024

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2024

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2024

Year:

2023

We investigated the impact of aging and exercise on extracellular matrix components of intramuscular connective tissue using proteomics. Middle-aged and old mice were subjected to three different levels of regular physical activity for 10 wk (high-resistance wheel running, low-resistance wheel running, or sedentary controls). We prepared extracts of extracellular matrix proteins depleted of cellular proteins. Our findings indicate that intramuscular connective tissue alters its soluble protein content with age but is unaffected by training.

Year:

2023

Year:

2023

Year:

2023

Collaborators (14)

Jason White

Charles Sturt University

AUSTRALIA
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Cameron Nowell

MONASH UNIVERSITY

AUSTRALIA
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S. P. Magnusson

-

DENMARK
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Khoon Lim

Prof.

University of Sydney

AUSTRALIA
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Michael Kjaer

-

DENMARK
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Avnika Ruparelia

Senior Lecturer/Group Leader

University of Melbourne

AUSTRALIA
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John Bateman

University of Melbourne

AUSTRALIA
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Ching-Yan Chloé Yeung

Lektor

Faculty of Health and Medical Sciences, University of Copenhagen

DENMARK
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Ritika Saxena

Murdoch Childrens Research Institute

AUSTRALIA
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Benjamin T. Cocanougher

Assistant Professor

Cincinnati Children's Hospital Medical Center

UNITED STATES
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Ed Stanley

Laboratory Head

Murdoch Childrens Research Institute

AUSTRALIA
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Valérie Allamand

Inserm Research Director / Team Leader

INSERM

FRANCE
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Eric Hanssen

Professor

University of Melbourne

AUSTRALIA
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Kathryn North

Group Leader, Neuromuscular Research; Chief Investigator, Australian Genomic Health Alliance

Murdoch Childrens Research Institute

AUSTRALIA
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