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Shireen Lamande
Has grant
Group Leader
Research Interests
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Recent Grants
Grant: Open
Replicating the cartilage micromechanical environment
Open Date: 2024-05-31
Close Date: 2027-05-30
Grant: Close
Rebalancing the proteostasis network with small molecule therapeutics to treat genetic skeletal diseases
Open Date: 2023-12-15
Close Date:
Grant: Close
Making a Niche: an in vitro human bone marrow organoid factory for blood
Open Date: 2021-11-04
Close Date:
Grant: Close
New therapeutic approaches for genetic skeletal disorders
Open Date: 2021-01-01
Close Date: 2023-12-01
Grant: Close
Skeletal Disease in a Dish: Using novel in vitro disease models produced from patient induced pluripotent stem cells to reveal pathogenic mechanisms and explore treatments for genetic skeletal disorders
Open Date: 2018-01-01
Close Date: 2020-01-01
Articles (12)
Year:
2025
Year:
2025
Year:
2025
Year:
2025
Year:
2024
Year:
2024
Year:
2024
Year:
2024
Year:
2023
We investigated the impact of aging and exercise on extracellular matrix components of intramuscular connective tissue using proteomics. Middle-aged and old mice were subjected to three different levels of regular physical activity for 10 wk (high-resistance wheel running, low-resistance wheel running, or sedentary controls). We prepared extracts of extracellular matrix proteins depleted of cellular proteins. Our findings indicate that intramuscular connective tissue alters its soluble protein content with age but is unaffected by training.
Year:
2023
Year:
2023
Year:
2023
Collaborators (14)
Jason White
Charles Sturt University
Cameron Nowell
MONASH UNIVERSITY
S. P. Magnusson
-
Khoon Lim
Prof.
University of Sydney
Michael Kjaer
-
Avnika Ruparelia
Senior Lecturer/Group Leader
University of Melbourne
John Bateman
University of Melbourne
Ching-Yan Chloé Yeung
Lektor
Faculty of Health and Medical Sciences, University of Copenhagen
Ritika Saxena
Murdoch Childrens Research Institute
Benjamin T. Cocanougher
Assistant Professor
Cincinnati Children's Hospital Medical Center
Ed Stanley
Laboratory Head
Murdoch Childrens Research Institute
Valérie Allamand
Inserm Research Director / Team Leader
INSERM
Eric Hanssen
Professor
University of Melbourne
Kathryn North
Group Leader, Neuromuscular Research; Chief Investigator, Australian Genomic Health Alliance
Murdoch Childrens Research Institute
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