Shozeb Haider

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Professor in Computational Biophysics

UCL School of Pharmacy

United Kingdom

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About

Dr. Shozeb Haider is a Professor in Computational Biophysics at University College London School of Pharmacy, United Kingdom. His research focuses on molecular interactions, protein dynamics, and the structural biology of transporters and antiviral mechanisms. Recent articles highlight his work on the functioning of enzymes at interfaces, as well as studies on the antioxidant responses in plants exposed to toxic materials.

Recent Grants

Grant: Close

Challenges in β lactamase mediate resistance

Open Date: 2019-02-01

Close Date: 2023-12-01

Grant: Close

Small molecule inhibitors of the anti-apoptotic FLIP-FADD protein-protein interaction for the treatment of non-small cell lung cancer

Open Date: 2012-12-01

Close Date: 2016-02-29

Grant: Close

Small molecule inhibitors of the anti-apoptotic FLIP-FADD protein-protein interaction for the treatment of non-small cell lung cancer

Open Date: 2012-08-01

Close Date: 2015-08-01

Grant: Close

Development of small molecule legumain inhibitors for treatment of poor prognosis cancer

Open Date: 2011-11-01

Close Date: 2012-11-01

Articles (20)

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2020

Collaborators (9)

Pratul Agarwal

Oklahoma State University

UNITED STATES

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Joanna Nowak-Karnowska

Adam Mickiewicz University in Poznań

POLAND

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Susanta Haldar

University of Bristol

UNITED KINGDOM

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Francesco Luigi Gervasio

Full Professor

University of Geneva

SWITZERLAND

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Zoë A. E. Waller

University College London

UNITED KINGDOM

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Mark Yarchoan

Johns Hopkins University

UNITED STATES

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Gary Parkinson

University College London

UNITED KINGDOM

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Se-Min Kim

Icahn School of Medicine at Mount Sinai

UNITED STATES

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Nikos Pinotsis

Birkbeck University of London

UNITED KINGDOM

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Shozeb Haider

Research Interests

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About

Recent Grants

Articles (20)

The interactions of 9-methoxyluminarine with Bcl-2 G-quadruplex

Insight into how PETase Functions at the Solid‐Liquid Interface and an Activity‐Stability Trade‐Off

Insight into how PETase Functions at the Solid‐Liquid Interface and an Activity‐Stability Trade‐Off

Cysteine Alleviates the Toxicity of Cadmium Telluride Quantum Dots (CdTe QDs) by Modulating the Antioxidant System and Root Metabolic Pathways in Rice

DNA-Programmable Protein Degradation: Dynamic Control of Proteolysis-Targeting Chimera Activity via DNA Hybridization and Strand Displacement

Exploiting functional regions in the viral RNA genome as druggable entities

Exploiting functional regions in the viral RNA genome as druggable entities

Conformational Landscape of the Di- and Tripeptide Permease A Transport Cycle

Structural Insights into the Substrate Egress Pathways Explains Specificity and Inhibition of Human Glucose Transporters (GLUT1 and GLUT9)

Impact of the double deletion ΔG242-T243 in KPC-2 in the effectiveness of ceftazidime-avibactam and imipenem-relebactam

Future COVID19 surges prediction based on SARS-CoV-2 mutations surveillance

Revealing druggable cryptic pockets in the Nsp1 of SARS-CoV-2 and other β-coronaviruses by simulations and crystallography

Two Ligand-Binding Sites on SARS-CoV-2 Non-Structural Protein 1 Revealed by Fragment-Based X-ray Screening

Triggered Assembly of a DNA-Based Membrane Channel

Mechanistic Insights into the Ligand-Induced Unfolding of an RNA G-Quadruplex

Structural basis of the effect of activating mutations on the EGF receptor

Conformational flexibility of A Highly Conserved Helix Controls Cryptic Pocket Formation in FtsZ

First-in-class humanized FSH blocking antibody targets bone and fat.

Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths

Role of in silico structural modeling in predicting immunogenic neoepitopes for cancer vaccine development

Collaborators (9)

Pratul Agarwal

Joanna Nowak-Karnowska

Susanta Haldar

Francesco Luigi Gervasio

Zoë A. E. Waller

Mark Yarchoan

Gary Parkinson

Se-Min Kim

Nikos Pinotsis

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