Zoë A. E. Waller

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University College London

United Kingdom

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Recent Grants

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New high resolution mass spectrometry facilities for macromolecules and metabolites at the University of East Anglia

Open Date: 2020-11-05

Close Date: 2021-04-03

Grant: Close

Epigenetic control of nitrous oxide emission by denitrifying bacteria

Open Date: 2019-11-01

Close Date: 2022-10-31

Grant: Close

Development of tools to investigate the role of DNA structures in diabetes

Open Date: 2018-10-01

Close Date: 2020-09-30

Grant: Close

New Gas Chromatography-Mass Spectrometry and Fluorescence facilities for the UEA Schools of Chemistry and Pharmacy

Open Date: 2018-09-30

Close Date: 2020-03-30

Grant: Close

Investigating DNA's Mysterious Structures (WALLER_U17DTP1)

Open Date: 2017-09-30

Close Date: 2021-09-29

Articles (14)

The potent G-quadruplex experimental drug QN-302 has strong opposing effects with i-motif DNA structures at the promoter of S100P .

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2024

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2021

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University of Sheffield

UNITED KINGDOM

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Rianne Lord

University of East Anglia

UNITED KINGDOM

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Masashi Minamino

The Francis Crick Institute

UNITED KINGDOM

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Shozeb Haider

Professor in Computational Biophysics

UCL School of Pharmacy

UNITED KINGDOM

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Kelly Irving

University in Western Australia

AUSTRALIA

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Cameron Evans

University of Western Australia

AUSTRALIA

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Christopher Morris

University of East Anglia

UNITED KINGDOM

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Zoë A. E. Waller

Research Interests

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Contact this professor

Recent Grants

Articles (14)

QN-302 demonstrates opposing effects between i-motif and G-quadruplex DNA structures in the promoter of the S100P gene

Prediction of DNA i-motifs via machine learning

QN-302 demonstrates opposing effects between i-motif and G-quadruplex DNA structures in the promoter of the S100P gene

Anticancer activity and DNA interaction of bis(pyridyl)allene-derived metal complexes

The Potent G-Quadruplex-Binding Compound QN-302 Downregulates S100P Gene Expression in Cells and in an In Vivo Model of Pancreatic Cancer

Replication‐induced DNA secondary structures drive fork uncoupling and breakage

Stability and context of intercalated motifs (i-motifs) for biological applications

Identification of sugar-containing natural products that interact with i-motif DNA

i-Motif formation and spontaneous deletions in human cells

Mechanistic Insights into the Ligand-Induced Unfolding of an RNA G-Quadruplex

Water-Soluble Heliomycin Derivatives to Target i-Motif DNA

Analysis of putative quadruplex-forming sequences in fungal genomes: novel antifungal targets?

Understanding the Potential In Vitro Modes of Action of Bis(β‐diketonato) Oxovanadium(IV) Complexes

Analysis of putative quadruplex-forming sequences in fungal genomes: Novel antifungal targets?

Collaborators (16)

Jessica King

Susanta Haldar

Ulrich Keyser

Francesco Luigi Gervasio

Stephen Neidle

Stefan Bidula

María Paz Muñoz

Nicole Smith

Yiliang Ding

Mahmoud Abdelhamid

Rianne Lord

Masashi Minamino

Shozeb Haider

Kelly Irving

Cameron Evans

Christopher Morris

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