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Sikander Hayat

Associate Professor

Icahn School of Medicine at Mount Sinai

United States

Research Interests

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Articles (20)

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2026

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2024

Collaborators (15)

Rafael Kramann

RWTH Aachen University

GERMANY

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Jeroen Demmers

Associate Professor | Director of the Proteomics Core Facility

Erasmus MC

NETHERLANDS

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Alexandre Paccalet

Project leader

Hospices Civils de Lyon

FRANCE

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R Foo

Professor

National University of Singapore (NUS)

SINGAPORE

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Yongjian Liu

Washington University in St. Louis

UNITED STATES

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Nadia Rosenthal

Professorial Fellow

Murdoch Childrens Research Institute

AUSTRALIA

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marian clahsen-van groningen

Guest Professorship

RWTH Aachen University

GERMANY

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Rahman Omidinia Anarkoli

DWI – Leibniz-Institut für Interaktive Materialien

GERMANY

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Frank Bengel

Ärzte

Hannover Medical School

GERMANY

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Julienne Carstens

University of Alabama, Tuscaloosa

UNITED STATES

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Nathan Stitziel

Professor

Washington University in Saint Louis School of Medicine

UNITED STATES

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Christoph Kuppe

Professor

RWTH Aachen University

GERMANY

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Kory J. Lavine

Washington University School of Medicine

UNITED STATES

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Essam Abdelalim

Joint Associate Professor

Hamad Bin Khalifa University

QATAR

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Paul Cheng

Stanford University

UNITED STATES

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Sikander Hayat

Research Interests

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Articles (20)

Targeting Modulated Vascular Smooth Muscle Cells in Atherosclerosis via FAP-Directed Immunotherapy

AI-driven discovery of GPNMB CAR T cells as a multi-cancer therapy

scDecorr: feature decorrelation based representation learning enables self-supervised alignment of multiple single-cell experiments.

A bioprinted and scalable model of human tubulo-interstitial kidney fibrosis

Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia.

Targeting endothelin A and angiotensin type 1 receptors with ambrisentan and losartan ameliorates cisplatin-induced injury in human tubuloids

GraphComm predicts cell cell communication using a graph based deep learning method in single cell RNA sequencing data

Encompassing view of spatial and single-cell RNA sequencing renews the role of the microvasculature in human atherosclerosis

Prospective Evaluation of Structure-Based Simulations Reveal Their Ability to Predict the Impact of Kinase Mutations on Inhibitor Binding

RFX3 is essential for the generation of functional human pancreatic islets from stem cells

Label-free single-cell RNA multiplexing leveraging genetic variability

Targeting immune-fibroblast cell communication in heart failure.

Matrix Metalloproteinase-7 in Urinary Extracellular Vesicles Identifies Rapid Disease Progression in Autosomal Dominant Polycystic Kidney Disease

Spatial transcriptomic analysis of primary and metastatic pancreatic cancers highlights tumor microenvironmental heterogeneity

Generation of a conditional cellular senescence model using proximal tubule cells and fibroblasts from human kidneys.

Deletion of RFX6 impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors.

ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury- responsive fibroblasts

Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling

Harnessing Artificial Intelligence for Enhanced Renal Analysis: Automated Detection of Hydronephrosis and Precise Kidney Segmentation

Novel YAP1/TAZ pathway inhibitors identified through phenotypic screening with potent anti-tumor activity via blockade of GGTase-I and Rho-GTPase signaling

Collaborators (15)

Rafael Kramann

Jeroen Demmers

Alexandre Paccalet

R Foo

Yongjian Liu

Nadia Rosenthal

marian clahsen-van groningen

Rahman Omidinia Anarkoli

Frank Bengel

Julienne Carstens

Nathan Stitziel

Christoph Kuppe

Kory J. Lavine

Essam Abdelalim

Paul Cheng

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