Simon Reed

Professor

Cardiff University School of Medicine

United Kingdom

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Simon Reed is a Professor at Cardiff University School of Medicine in the United Kingdom. His research focuses on DNA repair mechanisms, genomics, and the interactions of non-coding RNAs with key proteins. Recent articles by Professor Reed explore topics such as base excision repair, genome-wide Cas9 off-target activity, and the implications of DNA replication on mutational landscapes.

Articles (8)

Year:

2024

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2020

Collaborators (4)

Georgina Menzies

Lecturer

Cardiff University

UNITED KINGDOM

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Carole Yauk

Full Professor

University of Ottawa

CANADA

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Hanspeter Naegeli

Institute Head, Chair of Toxicology

University of Zurich

SWITZERLAND

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Jesse Salk

Clinical Assistant Professor

University of Washington

UNITED STATES

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Simon Reed

Research Interests

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Articles (8)

Long non-coding RNA LIP interacts with PARP-1 influencing the efficiency of base excision repair

Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology

Negative DNA supercoiling induces genome-wide Cas9 off-target activity.

To incise or not and where: SET-domain methyltransferases know.

DNA replication initiation shapes the mutational landscape and expression of the human genome.

Precision digital mapping of endogenous and induced genomic DNA breaks by INDUCE-seq

Carcinogen-induced DNA structural distortion differences in the RAS gene isoforms; the importance of local sequence

LRIK interacts with the Ku70-Ku80 heterodimer enhancing the efficiency of NHEJ repair.

Collaborators (4)

Georgina Menzies

Carole Yauk

Hanspeter Naegeli

Jesse Salk

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