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Sina Shadfar

Macquarie University

Australia

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Research Interests

Neurology

30%

Biochemistry

70%

Neurodegenerative Disease

70%

Amyotrophic Lateral Sclerosis

40%

Neuroprotection

40%

Protein Regulation

20%

Proteostasis

20%

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Articles16

The redox activity of protein disulphide isomerase functions in non-homologous end-joining repair to prevent DNA damage

Article Link

Year:

2025

Pathological forms of TDP-43 in amyotrophic lateral sclerosis (ALS) promote aberrant telomere elongation

Article Link

Year:

2025

C9orf72-associated dipeptide repeat expansions perturb ER-golgi vesicular trafficking, inducing golgi fragmentation and ER stress, in ALS/FTD

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Year:

2024

Molecular hallmarks of ageing in amyotrophic lateral sclerosis

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Year:

2024

Amyloid-beta and tau protein beyond Alzheimer's disease

Article Link

Year:

2024

Correction: Methanolic Extract of Boswellia serrata Gum Protects the Nigral Dopaminergic Neurons from Rotenone-Induced Neurotoxicity

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Year:

2024

Apolipoprotein ε in brain and retinal neurodegenerative diseases

Article Link

Year:

2023

Redox dysregulation as a driver for DNA damage and its relationship to neurodegenerative diseases

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Year:

2023

ALS/FTD-associated mutation in cyclin F inhibits ER-Golgi trafficking, inducing ER stress, ERAD and Golgi fragmentation

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Year:

2023

Ketone bodies mediate alterations in brain energy metabolism and biomarkers of Alzheimer’s disease

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Year:

2023

The role of sleep deprivation in streptozotocin-induced Alzheimer's disease-like sporadic dementia in rats with respect to the serum level of oxidative and inflammatory markers.

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Year:

2022

Methanolic Extract of Boswellia serrata Gum Protects the Nigral Dopaminergic Neurons from Rotenone-Induced Neurotoxicity

Article Link

Year:

2022

The Complex Mechanisms by Which Neurons Die Following DNA Damage in Neurodegenerative Diseases

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Year:

2022

Protein disulphide isomerase (PDI) is protective against amyotrophic lateral sclerosis (ALS)-related mutant Fused in Sarcoma (FUS) in in vitro models

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Year:

2021

Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations

Article Link

Year:

2020

The redox activity of protein disulfide isomerase inhibits ALS phenotypes in cellular and zebrafish models

Article Link

Year:

2020

Collaborators30

Marta Vidal

Macquarie University

AUSTRALIA

Ian Blair

Macquarie University

AUSTRALIA

Samran Sheriff

Macquarie University

AUSTRALIA

Cyril Jones Jagaraj

Macquarie University

AUSTRALIA

Angela Laird

Macquarie University

AUSTRALIA

Julie Atkin

Macquarie University

AUSTRALIA

Dominic Rowe

Macquarie University

AUSTRALIA

Paul Haynes

Macquarie University

AUSTRALIA

Sonam Parakh

Macquarie University

AUSTRALIA

Prachi Mehta

Macquarie University

AUSTRALIA

Mary-Louise Rogers

Flinders University

AUSTRALIA

Stephanie Rayner

Macquarie University

AUSTRALIA

Julie Hunter

Macquarie University

AUSTRALIA

Fabiha Farzana

Macquarie University

AUSTRALIA

Saravanabavan Sayanthooran

Macquarie University

AUSTRALIA

Anand Deva

Macquarie University

AUSTRALIA

Prita Riana Asih

Macquarie University

AUSTRALIA

Mehdi Mirzaei

Macquarie University

AUSTRALIA

Ghasem Hosseini Salekdeh

Professor in Systems Biology

Macquarie University

AUSTRALIA

Heidi Hillebrandt

Macquarie University

AUSTRALIA

Emily Don

Macquarie University

AUSTRALIA

Stuart Graham

Macquarie University

AUSTRALIA

Shu Yang

Macquarie University

AUSTRALIA

Sharlynn Wu

Macquarie University

AUSTRALIA

Garth Nicholson

Professor

AUSTRALIA

Vivek Gupta

Macquarie University

AUSTRALIA

Anna Konopka

Flinders University

AUSTRALIA

Pratishtha Chatterjee

Macquarie University

AUSTRALIA

Lezanne Ooi

University of Wollongong

AUSTRALIA

Albert Lee

Macquarie University

AUSTRALIA

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