Sophie Janssens

Full Professor

Ghent University

Belgium

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Research Interests

Immunology

100%

Cell Biology

100%

Inflammatory Biology

80%

T Cell Biology

60%

Macrophage Biology

50%

Immune Response

40%

Immune Regulation

30%

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Articles18

Type 1 immunity enables neonatal thymic ILC1 production

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Year:

2024

STE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity

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Year:

2023

LXR signaling controls homeostatic dendritic cell maturation

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Year:

2023

The IRE1β-mediated unfolded protein response is repressed by the chaperone AGR2 in mucin producing cells

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Year:

2023

Activation of goblet-cell stress sensor IRE1β is controlled by the mucin chaperone AGR2.

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Year:

2023

Decoding immunogenic cell death from a dendritic cell perspective.

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Year:

2023

Loss of function of XBP1 splicing activity of IRE1α favors B cell tolerance breakdown.

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Year:

2023

Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity.

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Year:

2023

Efficacy of CD40 agonists is mediated by distinct cDC subsets and subverted by suppressive macrophages

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Year:

2022

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

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Year:

2022

Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting

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Year:

2022

The STE20 kinase TAOK3 controls the development of house dust mite-induced asthma in mice.

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Year:

2021

IRE1β does not affect mucus secretion during allergic asthma development in a house dust mite murine model.

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Year:

2021

A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism.

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Year:

2021

Evolution and function of the epithelial cell-specific ER stress sensor IRE1β.

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Year:

2021

Molecular Evaluation of Endoplasmic Reticulum Homeostasis Meets Humoral Immunity.

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Year:

2021

The UPR sensor IRE1α promotes dendritic cell responses to control Toxoplasma gondii infection.

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Year:

2021

TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization.

Article Link

Year:

2020

Collaborators21

Damya Laoui

Vrije Universiteit Brussel

BELGIUM

Kim Deswarte

Universiteit Gent

BELGIUM

Isabelle Guillas

Associate professor

Sorbonne Université

FRANCE

Leonidas G Alexopoulos

tenured track professor

National Technical University of Athens

GREECE

Bruno Verstraeten

Ghent University

BELGIUM

Monica Vara-Perez

Vrije Universiteit Brussel

BELGIUM

Stijn Vanhee

Assistent Professor

Ghent University

BELGIUM

Abhishek Garg

Professor at KU Leuven

KU Leuven

BELGIUM

Sofie Deschoemaeker

Vrije Universiteit Brussel

BELGIUM

Bart N. Lambrecht

Ghent University

BELGIUM

David Ron

Lab Head (Professor)

University of Cambridge

UNITED KINGDOM

Gert Van Isterdael

BELGIUM

Aleksandar Murgaski

Vrije Universiteit Brussel

BELGIUM

Daliya Kancheva

Vrije Universiteit Brussel

BELGIUM

Peter Tougaard

Ghent University

BELGIUM

SANA ARNOUK

Vrije Universiteit Brussel

BELGIUM

Anneleen Remmerie

Universiteit Gent

BELGIUM

Sabrina Marion

Associated Professor, team leader

FRANCE

Els Duval

Antwerp University Hospital

BELGIUM

Helena Van Damme

Vrije Universiteit Brussel

BELGIUM

Eva Hadadi

Vrije Universiteit Brussel

BELGIUM

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