Sophie Kellaway

Assistant Professor

University of Nottingham

United Kingdom

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Sophie Kellaway is an Assistant Professor at the University of Nottingham, UK. Her research areas encompass leukemic stem cell biology, gene regulation in acute myeloid leukemia, and the molecular mechanisms underlying hematological diseases. Recent publications include studies on targeting signaling pathways in leukemia and understanding the gene regulatory networks involved in disease progression.

Articles (10)

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2025

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2025

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2024

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2024

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2024

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2023

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2023

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2023

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2022

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2022

Collaborators (10)

Lisa Russell

Senior Lecturer in Childhood Cancer and Haematology

Newcastle University

UNITED KINGDOM

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Jean-Baptiste Cazier

Director, Professor of Bioinformatics

University of Birmingham

UNITED KINGDOM

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Constanze Bonifer

University of Birmingham

UNITED KINGDOM

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Luke Ames

University of Birmingham

UNITED KINGDOM

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Head of DCAL, PhD

Goethe University Frankfurt

GERMANY

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Sophie Kellaway

Research Interests

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Articles (10)

How to drug a leukemic stem cell: deciphering heterogeneity for better specificity

Targeting growth signals in leukemia: A case of mistaken identity

Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth

Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1

A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification.

Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia.

Molecular Basis of Hematological Disease Caused by Inherited or Acquired RUNX1 Mutations

Collaborators (10)

Lisa Russell

Jean-Baptiste Cazier

Constanze Bonifer

Luke Ames

Simon Bomken

Peter Keane

James Allan

Venetia Bigley

Deepali Pal

Claus Meyer

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