Stefanie M. Kaiser

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Ludwig-Maximilians-Universität München

Germany

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Recent Grants

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Dynamic nature of RNA modifications and their influence in neurological diseases

Open Date: 2017-01-01

Close Date:

Grant: Close

Quantification and Characterisation of the DNA phosphorothioate modification in the gut microbiome

Open Date: 2013-01-01

Close Date: 2016-12-31

Articles (20)

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Collaborators (5)

Carine Tisne

CNRS

FRANCE

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Matthias Schaefer

Associate Professor

Medical University of Vienna

AUSTRIA

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Dragony Fu

Associate Professor

University of Rochester

UNITED STATES

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Pierre Barraud

Université Paris Cité

FRANCE

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Henning Jessen

Professor of Bioorganic Chemistry

University of Freiburg

GERMANY

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Stefanie M. Kaiser

Research Interests

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Recent Grants

Articles (20)

Temporal and spatial profiling of ALKBH5 activity through NAIL-MS and compartmentalized RNA Isolation

Direct RNA sequencing of the Escherichia coli epitranscriptome uncovers alterations under heat stress

Chemical nucleases are a robust alternative for RNase H cleavage of human ribosomal RNA

Chemical reactivity of RNA and its modifications with hydrazine

NAIL-MS reveals tRNA and rRNA hypomodification as a consequence of 5-fluorouracil treatment

tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus

Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs

Amyloid pathology reduces ELP3 expression and tRNA modifications leading to impaired proteostasis

Structural basis of tRNA recognition by the m<sup>3</sup>C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase

Sangivamycin is preferentially incorporated into viral RNA by the SARS-CoV-2 polymerase

Different modification pathways for m1A58 incorporation in yeast elongator and initiator tRNAs

Temporal resolution of NAIL-MS of tRNA, rRNA and Poly-A RNA is overcome by actinomycin D

Temporal resolution of NAIL-MS of tRNA, rRNA and Poly-A RNA is overcome by actinomycin D

Instrumental analysis of RNA modifications

Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo

Production and purification of endogenously modified tRNA-derived small RNAs

Broadly applicable oligonucleotide mass spectrometry for the analysis of RNA writers and erasers in vitro

Synthesis and Metabolic Fate of 4‐Methylthiouridine in Bacterial tRNA

Synthese von Galaktosyl‐Queuosin und Verteilung von hypermodifizierten Q‐Nukleosiden in Mausgeweben

Synthesis of Galactosyl‐Queuosine and Distribution of Hypermodified Q‐Nucleosides in Mouse Tissues

Collaborators (5)

Carine Tisne

Matthias Schaefer

Dragony Fu

Pierre Barraud

Henning Jessen

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