Steffen Pockes

University of Regensburg

Germany

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Articles (23)

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2024

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2021

Collaborators (6)

Bradley Hoare

University of Melbourne

AUSTRALIA

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Katarzyna Szczepańska

Institute of Pharmacology

POLAND

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David Reiner-Link

Københavns Universitet

DENMARK

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Enrique José Cobos Del Moral

Universidad de Granada

SPAIN

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Barry Finzel

University of Minnesota

UNITED STATES

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Ulrich Gergs

Martin Luther University Halle-Wittenberg

GERMANY

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Steffen Pockes

Research Interests

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Articles (23)

Activation of Multiple G Protein Pathways to Characterize the Five Dopamine Receptor Subtypes Using Bioluminescence Technology

Conditional Cell-Penetrating Peptide Exposure as Selective Nanoparticle Uptake Signal

Initial Characterization of a Transgenic Mouse with Overexpression of the Human H<sub>1</sub>-Histamine Receptor on the Heart

Cryo-EM structure of cell-free synthesized human histamine 2 receptor/Gs complex in nanodisc environment

Dual Piperidine-Based Histamine H<sub>3</sub> and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.

Ergometrine stimulates histamine H2 receptors in the isolated human atrium

Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3

Discovery of a Tritiated Radioligand with High Affinity and Selectivity for the Histamine H<sub>3</sub> Receptor

Fluorescent Tools for the Imaging of Dopamine D2‐Like Receptors

Shedding Light on the D1‐Like Receptors: A Fluorescence‐Based Toolbox for Visualization of the D1 and D5 Receptors

An electrophilic fragment screening for the development of small molecules targeting caspase-2

Clonidine stimulates force of contraction via histamine H2 receptors in the human atrium

Lysergic acid diethylamide stimulates cardiac human H2 histamine and cardiac human 5-HT4-serotonin receptors

Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis

Structure-Based Design and Biological Evaluation of Novel Caspase-2 Inhibitors Based on the Peptide AcVDVAD-CHO and the Caspase-2-Mediated Tau Cleavage Sequence YKPVD314

Targeting caspase-2 interactions with tau in Alzheimer's disease and related dementias

Investigating the ligand agonism and antagonism at the D2long receptor by dynamic mass redistribution

Caspase-2 Inhibitor Blocks Tau Truncation and Restores Excitatory Neurotransmission in Neurons Modeling FTDP-17 Tauopathy

Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H<sub>3</sub> and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties.

Cardiac effects of novel histamine H2 receptor agonists

A Versatile Sub-Nanomolar Fluorescent Ligand Enables NanoBRET Binding Studies and Single-Molecule Microscopy at the Histamine H3 Receptor

Abolishing Dopamine D2long/D3 Receptor Affinity of Subtype-Selective Carbamoylguanidine-Type Histamine H2 Receptor Agonists

Histamine H2 receptor radioligands: triumphs and challenges

Collaborators (6)

Bradley Hoare

Katarzyna Szczepańska

David Reiner-Link

Enrique José Cobos Del Moral

Barry Finzel

Ulrich Gergs

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