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Stephanie Xie

Assistant Professor

University of Toronto

Canada

Research Interests

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Articles (20)

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2026

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2026

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2025

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2025

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2025

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2025

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2024

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2024

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2024

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2023

Collaborators (20)

Michael Rauh

Associate Professor and Attending Hematopathologist

CANADA

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Andy Zeng

University of Toronto

CANADA

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Brandon Hadland

Associate Professor

Fred Hutchinson Cancer Research Center

UNITED STATES

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Stefano Comazzetto

University of Edinburgh

UNITED KINGDOM

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Anniina Färkkilä

University of Helsinki

FINLAND

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Nicolò Gualandi

San Raffaele Telethon Institute for Gene Therapy

ITALY

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Adam Durbin

Assistant Member

St. Jude Children's Research Hospital

UNITED STATES

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Yongran Yan

University Health Network

CANADA

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Ryan Schreiner

Assistant Professor

Weill Cornell Medicine

UNITED STATES

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Tomer Itkin

Senior Lecturer (Assistant Professor)

Tel Aviv University

ISRAEL

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Emanuele Lettera

Senior Scientist

European Institute of Oncology

ITALY

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Zuzana Keckesova

Principal Investigator

Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

CZECH REPUBLIC

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Daniele Canarutto

Vita-Salute San Raffaele University

ITALY

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John R. Prensner

UNITED STATES

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Elvin Wagenblast

Assistant Professor

Icahn School of Medicine at Mount Sinai

UNITED STATES

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Stephanie Georgina Dakin

Full Professor of Musculoskeletal Sciences

University of Oxford

UNITED KINGDOM

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Diego Gilioli

Columbia University Irving Medical Center

UNITED STATES

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Edmond Chan

Columbia University Irving Medical Center

UNITED STATES

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Raffaella Molteni

Senior Research Scientist

Ospedale San Raffaele

ITALY

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Yang Lin

Assistant Professor

Weill Cornell Medicine

UNITED STATES

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Stephanie Xie

Research Interests

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Articles (20)

Molecular and phenotypic blueprint of human hematopoiesis links proliferation stress to stem cell aging

Intracellular IL-23R is necessary for mitotic spindle formation and viability in AML

Melatonin, circadian metabolism, mitochondrial remodeling, and cell size dynamics in primitive hematopoietic stem cells.

Human haematopoietic stem cells remember inflammatory stress

ATP2B1 expression identifies human hematopoietic stem cells with superior repopulation and self-renewal.

Ex Vivo Expansion of Hematopoietic Stem and Progenitor Cells from Human Mobilized Peripheral Blood for Gene Therapy Applications

Insights on Future Directions in Cancer Research from the 2025 AACR NextGen Stars

Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing

Extracellular Vesicles Define Discrete Nano-Based Niches Within the Human Haematopoietic System.

Mechanisms of hematopoietic clonal dominance in VEXAS syndrome

Senescence and inflammation are unintended adverse consequences of CRISPR-Cas9/AAV6-mediated gene editing in hematopoietic stem cells

Ascorbate deficiency increases quiescence and self-renewal in hematopoietic stem cells and multipotent progenitors.

Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs.

Context and timing matters in acute myeloid leukemia: females are the superior hosts.

IRE1α–XBP1 moonlighting to restrict leukemia

ATP2B1 expression identifies human hematopoietic stem cells across ontogeny with superior repopulation and self-renewal capacity

Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging.

Distinct gene regulatory networks govern hematopoietic and leukemia stem cells

Metformin reduces the clonal fitness of Dnmt3aR878H hematopoietic stem and progenitor cells by reversing their aberrant metabolic and epigenetic state

Sphingolipids and HSC fitness: enigma no more

Collaborators (20)

Michael Rauh

Andy Zeng

Brandon Hadland

Stefano Comazzetto

Anniina Färkkilä

Nicolò Gualandi

Adam Durbin

Yongran Yan

Ryan Schreiner

Tomer Itkin

Emanuele Lettera

Zuzana Keckesova

Daniele Canarutto

John R. Prensner

Elvin Wagenblast

Stephanie Georgina Dakin

Diego Gilioli

Edmond Chan

Raffaella Molteni

Yang Lin

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