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Stephen C. Mack

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Associate Member

Baylor College of Medicine

United States

Research Interests

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Recent Grants

Grant: Close

Interrogating Chromatin States to Pinpoint the Cellular Origins and Therapeutic Targets in Pediatric Brain Tumours

Open Date: 2017-09-01

Close Date: 2021-08-01

Grant: Close

Interrogating the enhancer landscape of ependymoma to inform novel therapies

Open Date: 2016-06-01

Close Date: 2019-05-01

Grant: Close

Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma

Open Date: 2012-01-01

Close Date: 2012-03-31

Grant: Close

Identification of novel ependymoma tumour suppressor genes by genome-wide DNA methylation profiling.

Open Date: 2010-05-01

Close Date: 2013-04-30

Articles (12)

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2025

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2025

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2022

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Full professor

Erasmus MC

NETHERLANDS

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John Joo Yiul Lee

Harvard University

UNITED STATES

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Siri M Ippagunta

West Virginia University

UNITED STATES

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Alexandre Carisey

Microscopy core director

St. Jude Children's Research Hospital

UNITED STATES

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Assistant Professor

Indian Institute of Technology, Roorkee

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Dan G. Duda

Associate Professor

UNITED STATES

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Antony Michealraj Kulandai Manuvel

Assistant Professor (Tenure-Track)

University of Pittsburgh

UNITED STATES

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ApplyKite TwinLearns as you apply

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Stephen C. Mack

Research Interests

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Recent Grants

Articles (12)

Targeting EPHB2/ABL1 restores antitumor immunity in preclinical models of ependymoma

B7-H3 CAR T Cells Are Effective against Ependymomas but Limited by Tumor Size and Immune Response

ZIC1 is a context-dependent medulloblastoma driver in the rhombic lip

Synthetic ZFTA fusions pinpoint disordered protein domain acquisition as a mechanism of brain tumorigenesis

A forward genetic screen identifies potassium channel essentiality in SHH medulloblastoma maintenance.

Combined targeting of glioblastoma stem cells of different cellular states disrupts malignant progression

Erratum: Correction: Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma (The Journal of experimental medicine (2019) 216 5 PII: e2019019605052025C DOI: 10.1084/jem.20190196.)

Infiltrating plasma cells maintain glioblastoma stem cells through IgG-Tumor binding

A Molecular Blueprint to Targeting ALK Gene Fusions in Glioblastoma

Leveraging epigenomic patterns to resolve the heterogeneity and origins of CNS germ cell tumors

Weighing ependymoma as an epigenetic disease

Invited Review: The role and contribution of transcriptional enhancers in brain cancer

Collaborators (17)

Adam Dupuy

Jian Xu

Kathleen Joyce Millen

Craig Daniels

Kelsey Caitlan Bertrand

Pim French

John Joo Yiul Lee

Siri M Ippagunta

Alexandre Carisey

Zohreh Amoozgar

Ali G Saad

Marco Gallo

Branden Moriarity

Mathieu Lupien

Devesh Bhimsaria

Dan G. Duda

Antony Michealraj Kulandai Manuvel

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