Stephen J. Keely
IrelandResearch Interests
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Articles (1)
Activation of the nuclear bile acid receptor, farnesoid X receptor (FXR), specifically upregulates ACE2 expression in undifferentiated colonic epithelial cells and inhibits virus-induced proinflammatory cytokine release. By virtue of these actions FXR represents a promising target for the development of new approaches to prevent intestinal manifestations of SARS-CoV-2 infection.
Year:
2023
Collaborators (1)
Paul Dawson
Emory University School of Medicine
UNITED STATES
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