Paul Dawson

Emory University School of Medicine

United States

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Articles (12)

Year:

2025

Year:

2024

Year:

2024

Year:

2023

Activation of the nuclear bile acid receptor, farnesoid X receptor (FXR), specifically upregulates ACE2 expression in undifferentiated colonic epithelial cells and inhibits virus-induced proinflammatory cytokine release. By virtue of these actions FXR represents a promising target for the development of new approaches to prevent intestinal manifestations of SARS-CoV-2 infection.

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2020

Collaborators (5)

Ryan Purcell

Assistant Professor

Emory University School of Medicine

UNITED STATES

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Stephen J. Keely

IRELAND

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Dean Jones

Professor

Emory University

UNITED STATES

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Lin Jia

University of Texas at Dallas

UNITED STATES

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Michael Trauner

Professor of Medicine and Chair of Gastroenterology and Hepatology

Medical University of Vienna

AUSTRIA

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Paul Dawson

Research Interests

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Articles (12)

Benefits and challenges to therapeutic targeting of bile acid circulation in cholestatic liver disease

Hepatic bile acid accretion correlates with cholestatic liver injury and therapeutic response in Cyp2c70 knockout mice with a humanized bile acid composition

BiliQML: a supervised machine-learning model to quantify biliary forms from digitized whole slide liver histopathological images

SLC51 family of steroid-derived molecule transporters in GtoPdb v.2023.1

Farnesoid X receptor enhances epithelial ACE2 expression and inhibits virally induced IL-6 secretion: implications for intestinal symptoms of SARS-CoV-2

Liver-restricted deletion of the biliary atresia candidate gene Pkd1l1 causes bile duct dysmorphogenesis and ciliopathy

Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury

Metabolic effects of the schizophrenia-associated 3q29 deletion

Alan Hofmann (1931‐2021): A career well spent understanding bile acids

NPC1L1 Deficiency Suppresses Ileal Fibroblast Growth Factor 15 Expression and Increases Bile Acid Pool Size in High-Fat-Diet-Fed Mice

SLC51 family of steroid-derived molecule transporters in GtoPdb v.2021.3

SLC51 family of steroid-derived molecule transporters (version 2020.4) in the IUPHAR/BPS Guide to Pharmacology Database

Collaborators (5)

Ryan Purcell

Stephen J. Keely

Dean Jones

Lin Jia

Michael Trauner

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