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Susana Valente

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Professor & Chair

The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology

United States

Research Interests

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Professors in United States Professors in Immunology Immunology professors in United States

Recent Grants

Grant: Open

Therapeutic Disruption of HIV Transcription by HIV-1 Tat Protein-Degrading Molecules

Open Date: 2025-08-06

Close Date: 2030-07-31

Grant: Open

Exploration of novel block-and-lock agents alone and in combination for HIV remission in humanized mice

Open Date: 2023-03-20

Close Date: 2028-02-29

Grant: Close

Development and characterization of HIV-1 Tat degraders

Open Date: 2022-05-01

Close Date: 2023-04-30

Grant: Open

Evaluation of didehydro-Cortistatin A as a block-and-lock agent for a functional HIV cure in a macaque model

Open Date: 2021-09-20

Close Date: 2027-08-31

Grant: Close

HOPE - HIV Obstruction by Programmed Epigenetics

Open Date: 2021-08-16

Close Date: 2026-04-30

Articles (18)

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Collaborators (14)

Douglas Nixon

Professor of Immunology in Medicine

Weill Cornell Medicine

UNITED STATES

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Robert Furler O'Brien

Associate Professor

Feinstein Institute for Medical Research

UNITED STATES

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Stéfano Cirigliano

Assistant Professor of Research

Weill Cornell Medicine

UNITED STATES

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Ursula Schulze-Gahmen

Gladstone Institutes

UNITED STATES

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Cedric Feschotte

Professor

Cornell University

UNITED STATES

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Avindra Nath

Clinical Director

National Institutes of Health

UNITED STATES

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Hyeryun Choe

Boston Children's Hospital

UNITED STATES

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Michael Farzan

Professor and Director of Virology Research

Boston Children's Hospital

UNITED STATES

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Chuan Li

Research Asisstant Professor

The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology

UNITED STATES

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Melanie Ott

Professor

University of California, San Francisco

UNITED STATES

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Mahmud Arif

Assistant Professor

Pennsylvania State University

UNITED STATES

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Lishomwa Ndhlovu

Professor

Weill Cornell Medical College

UNITED STATES

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Luisa Mori

Assistant Professor

Williams College

UNITED STATES

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Pauline Sameshima

Professor

Lakehead University

CANADA

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Susana Valente

Research Interests

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Recent Grants

Articles (18)

Quantitative limits of host-driven HIV transcription and host gene control by the viral transactivator Tat

Halting Recombinant Adeno-Associated Virus Transgene Expression Using mRNA-Lipid Nanoparticle-Delivered Meganucleases

The human chromatin remodeling complex p400 restricts HIV-1 transcription in a Tat-dependent manner

Combining spironolactone to antiretroviral therapy accelerates HIV decay in humanized mice.

The p400 complex promotes HIV-1 latency by suppressing viral transcription and altering the host cell state

FUBP3 enhances HIV-1 transcriptional activity and regulates immune response pathways in T cells

Human chromatin remodelers regulating HIV-1 transcription: a target for small molecule inhibitors

Erratum: FUBP3 enhances HIV-1 transcriptional activity and regulates immune response pathways in T cells.

Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model.

Persistent neuroinflammation in HIV-1 infected brain organoid models treated with antiretroviral therapy

Silencing the transcriptionally active HIV reservoir to improve treatment outcomes

Transcriptional and methylation outcomes of didehydro-cortistatin A use in HIV-1–infected CD4<sup>+</sup>T cells

Transcriptional regulation of the HIV-1 inhibitory factor human mannose receptor 1 by the myeloid-specific transcription factor PU.1

HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing

The chaperone protein p32 stabilizes HIV-1 Tat and strengthens the p-TEFb/RNAPII/TAR complex promoting HIV transcription elongation

The role of high cholesterol in SARS-CoV-2 infectivity

HIV-1 transcriptional modulation: novel host factors and prospective therapeutic strategies

Loss of In Vivo Replication Fitness of HIV-1 Variants Resistant to the Tat Inhibitor, dCA

Collaborators (14)

Douglas Nixon

Robert Furler O'Brien

Stéfano Cirigliano

Ursula Schulze-Gahmen

Cedric Feschotte

Avindra Nath

Hyeryun Choe

Michael Farzan

Chuan Li

Melanie Ott

Mahmud Arif

Lishomwa Ndhlovu

Luisa Mori

Pauline Sameshima

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