Susanna Brighenti

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Karolinska Institutet

Sweden

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Recent Grants

Grant: Close

Discovery of epigenetic modulators designed to treat and cure different tuberculosis endotypes by improving antimicrobial cellular immunity

Open Date: 2023-01-01

Close Date: 2025-12-01

Grant: Open

Immune Profiling and Immune checkpoint modulation of Multidrug-resistant tuberculosis infection (IPIM)

Open Date: 2023-01-01

Close Date: 2026-12-01

Grant: Close

Discovery of epigenetic modulators designed to treat and cure different tuberculosis endotypes by improving antimicrobial cellular immunity

Open Date: 2023-01-01

Close Date: 2025-12-01

Grant: Close

Exploring epigenetic alterations of cellular immunity in multidrug-resistant tuberculosis with relevance for new therapy using epigenetic- and immune-modulating drugs

Open Date: 2020-01-01

Close Date: 2023-12-01

Grant: Close

Mot två-stegs kombinationsbehandling med preparat som har epigenetiska- och immun-modulerande egenskaper som kan stödja utläkning av samt förhindra utveckling av antibiotika resistent tuberkulos

Open Date: 2020-01-01

Close Date: 2022-12-31

Articles (15)

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2021

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2021

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2020

Collaborators (18)

Johan K. Sandberg

Professor

Karolinska Institutet

SWEDEN

Susanna Brighenti

Research Interests

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Recent Grants

Articles (15)

Dual GSK-3β/HDAC Inhibitors Enhance the Efficacy of Macrophages to Control Mycobacterium tuberculosis Infection

Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19.

A successful UN High-Level Meeting on antimicrobial resistance must build on the 2023 UN High-Level Meeting on tuberculosis

The HLA-B -21 M/T dimorphism associates with disease severity in COVID-19.

Targeted plasma proteomics reveals signatures discriminating COVID-19 from sepsis with pneumonia

Immune cell landscape in symptomatic and asymptomatic SARS-CoV-2 infected adults and children in urban Dhaka, Bangladesh

Inflammatory immune profiles associated with disease severity in pulmonary tuberculosis patients with moderate to severe clinical TB or anemia.

Anemia Is a Strong Predictor of Wasting, Disease Severity, and Progression, in Clinical Tuberculosis (TB)

Reinventing the human tuberculosis (TB) granuloma: Learning from the cancer field

High Glucose and Carbonyl Stress Impair HIF-1-Regulated Responses and the Control of Mycobacterium tuberculosis in Macrophages

Immunosuppressive Features of the Microenvironment in Lymph Nodes Granulomas from Tuberculosis and HIV-Co-Infected Patients.

Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity

SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation

Immunomodulatory Agents Combat Multidrug-Resistant Tuberculosis by Improving Antimicrobial Immunity.

Slow radiological improvement and persistent low-grade inflammation after chemotherapy in tuberculosis patients with type 2 diabetes.

Collaborators (18)

Johan K. Sandberg

Alvaro Haroun-Izquierdo

Emma Ringqvist

Laura Marcela Palma Medina

Helena Bergsten

Olav Rooyackers

Isabel María Díaz Lozano

John Tyler Sandberg

Malin Flodström Tullberg

Sebastien Gagneux

Laura Rivino

Lars Frelin

Peter Bergman

Niklas Björkström

Jonas Klingstrom

Maria Lerm

Ebba Sohlberg

Andrea Ponzetta

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