Séverine Lamon

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Deakin University

Australia

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Recent Grants

Grant: Close

Can exercise slow down the epigenetic ageing clock?

Open Date: 2020-01-01

Close Date: 2022-12-31

Grant: Close

Project DE150100538

Open Date: 2015-01-01

Close Date: 2017-12-31

Grant: Close

EPO as a therapeutic agent to protect against muscle atrophy

Open Date: 2011-10-01

Close Date: 2012-03-31

Grant: Close

EPO as a therapeutic agent to protect against muscle atrophy

Open Date: 2010-10-01

Close Date: 2011-09-30

Articles (20)

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2025

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2025

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2024

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2024

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2024

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2024

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2024

Calcium is essential for signaling, excitation contraction, and energy homeostasis in the heart. Despite this, molecular regulators of these processes are not completely understood. We report that knockdown of lncRNA Tug1 alters the calcium handling transcriptome and increases mitochondrial calcium uniporter expression via a mechanism involving CaMKII. As overexpression of MCU is known to be protective against pathological cardiac remodeling, targeting Tug1 may be a potential strategy for treating cardiovascular disease.

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2023

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2023

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2023

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2021

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2021

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2021

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2021

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (12)

Mark Ziemann

Head of Bioinformatics

Burnet Institute

AUSTRALIA

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Angus Lindsay

AUSTRALIA

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Linpeng Fan

University of Melbourne

AUSTRALIA

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Livia Hool

University of Western Australia

AUSTRALIA

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Greg Kowalski

Senior Lecturer & Researcher

Deakin University Faculty of Health

AUSTRALIA

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Bronwyn M. Graham

University of New South Wales

AUSTRALIA

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Christopher Fry

Associate Professor

University of Kentucky

UNITED STATES

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Jessica Silver

Associate Lecturer in Exercise and Sport Science

Deakin University

AUSTRALIA

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Glenn Wadley

Professor (Exercise Metabolism), Associate Head of School (Research; 2018 onwards)

Deakin University

AUSTRALIA

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Sue Haupt

The George Institute for Global Health

AUSTRALIA

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Mirana Ramialison

Head of the Transcriptomics and Bioinformatics Group

Murdoch Childrens Research Institute

AUSTRALIA

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Sarah E. Alexander

AUSTRALIA

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Séverine Lamon

Research Interests

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Recent Grants

Articles (20)

ACTN3 genotype influences androgen response in developing murine skeletal muscle

The power – and complexity – of policy to drive advances in women’s health

Physiology: A perspective from the Australian experience

Direction-aware functional class scoring enrichment analysis of infinium DNA methylation data

The interactive effect of sustained sleep restriction and resistance exercise on skeletal muscle transcriptomics in young females

Bioavailable testosterone and androgen receptor activation, but not total testosterone, are associated with muscle mass and strength in females.

Single-session measures of quadriceps neuromuscular function are reliable in healthy females and unaffected by age.

Regulation of mitochondrial calcium uniporter expression and calcium-dependent cell signaling by lncRNA <i>Tug1</i> in cardiomyocytes

Muscle miRNAs are influenced by sex at baseline and in response to exercise.

Sex differences in muscle protein expression and DNA methylation in response to exercise training.

Striated muscle activator of Rho signalling (STARS) overexpression in the mdx mouse enhances muscle functional capacity and regulates the actin cytoskeleton and oxidative phosphorylation pathways.

The effect of sex hormones on skeletal muscle adaptation in females.

Total testosterone is not associated with lean mass or handgrip strength in pre-menopausal females.

Constructing 3D Macroporous Microfibrous Scaffolds with a Featured Surface by Heat Welding and Embossing.

Leucine augments specific skeletal muscle mitochondrial respiratory pathways during recovery following 7 days of physical inactivity in older adults.

The effect of acute sleep deprivation on skeletal muscle protein synthesis and the hormonal environment.

An obesogenic maternal environment impairs mouse growth patterns, satellite cell activation, and markers of postnatal myogenesis

Countering disuse atrophy in older adults with low-volume leucine supplementation.

Circulating microRNAs: let’s not waste the potential

Extracellular vesicular miRNA expression is not a proxy for skeletal muscle miRNA expression in males and females following acute, moderate intensity exercise

Collaborators (12)

Mark Ziemann

Angus Lindsay

Linpeng Fan

Livia Hool

Greg Kowalski

Bronwyn M. Graham

Christopher Fry

Jessica Silver

Glenn Wadley

Sue Haupt

Mirana Ramialison

Sarah E. Alexander

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