Takeharu Nagai

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Japan

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About

Takeharu Nagai is a Professor at TAKEHARU NAGAI in Japan. His research focuses on genetically encoded tools for studying cell-cell interactions, bioluminescence detection methods, and the development of advanced fluorescent proteins for bioimaging. Recent articles highlight his contributions to understanding brain connectivity and optimizing fluorescent indicators for biological applications.

Recent Grants

Grant: Close

Development of optical probes and actuators to investigate singularity cells

Open Date: 2018-06-29

Close Date: 2023-03-31

Grant: Close

Singularity biology

Open Date: 2018-06-29

Close Date: 2023-03-31

Grant: Close

Development of molecular probes and photo manipulation tools - Technologies for visualization and control of small number of biomolecules

Open Date: 2011-04-01

Close Date: 2016-03-31

Grant: Close

Spying minority in biological phenomena -Toward bridging dynamics between individual and ensemble processes-

Open Date: 2011-04-01

Close Date: 2016-03-31

Grant: Close

Effect of FAEEs on intracellular signalling

Open Date: 2011-01-01

Close Date: 2013-12-31

Articles (24)

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2021

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2021

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2021

Collaborators (11)

Yuki Hiruta

Keio University

JAPAN

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Yutaka Shindo

Associate professor

Kitasato University

JAPAN

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Kenta Temma

Assistant Professor

Osaka University

JAPAN

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Tomoki Matsuda

Osaka University

JAPAN

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Natsumi Hoshino

Assistant Professor

Osaka University

JAPAN

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Kiwamu Takemoto

Professor

Mie university

JAPAN

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Yasuhiro Kamei

特任教授（RMC教授）/RMC Professor

基礎生物学研究所/National Institute for Basic Biology

JAPAN

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Takashi Kanadome

National Institute for Basic Biology

JAPAN

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Kei-ichi Okazaki

准教授/Associate Professor

JAPAN

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Cong Quang Vu

Assistant Professor

Kanazawa University

JAPAN

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Toshiki Kubo

Specially Appointed Assistant Professor

Osaka University

JAPAN

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Takeharu Nagai

Research Interests

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About

Recent Grants

Articles (24)

Genetically encoded tools for Cell–Cell interactions underlying brain connectivity

Ratiometric bioluminescent detection of Cu(II) ion based on differences in enzymatic reaction kinetics of two luciferase variants

Positive-Type Reversibly Photoswitching Red Fluorescent Protein for Dual-Color Superresolution Imaging with Single Light Exposure for Off-Switching

Creating coveted bioluminescence colors for simultaneous multi-color bioimaging

Genetically encoded bioluminescent glucose indicator for biological research

Genetically-encoded temperature indicators for thermal biology

Calcium-induced upregulation of energy metabolism heats neurons during neural activity

High-affinity tuning of single fluorescent protein-type indicators by flexible linker length optimization in topology mutant

Extremely Sensitive Genetically Encoded Temperature Indicator Enabling Measurement at the Organelle Level

Optical inactivation of intracellular molecules by fast-maturating photosensitizing fluorescence protein, HyperNova

Improvement of the Green–Red Förster Resonance Energy Transfer-Based Ca2+ Indicator by Using the Green Fluorescent Protein, Gamillus, with a Trans Chromophore as the Donor

Near-infrared PAINT localization microscopy via chromophore replenishment of phytochrome-derived fluorescent tag

Editorial: Singularity Biology and Beyond

Autonomous multicolor bioluminescence imaging in bacteria, mammalian, and plant hosts

Joule heating involving ion currents through channel proteins

Intracellular Heat Transfer and Thermal Property Revealed by Kilohertz Temperature Imaging with a Genetically Encoded Nanothermometer

Development of intensiometric indicators for visualizing N-cadherin interaction across cells

Structure‐based analysis and evolution of a monomerized red‐colored chromoprotein from the Olindias formosa jellyfish

Extension of the short wavelength side of fluorescent proteins using hydrated chromophores, and its application

Application of Green‐enhanced Nano‐lantern as a bioluminescent ratiometric indicator for measurement of Arabidopsis thaliana root apoplastic fluid pH

Tiny but bright

Ratiometric Bioluminescent Indicator for a Simple and Rapid Measurement of Thrombin Activity Using a Smartphone

Visible-Wavelength Multiphoton Activation Confocal Microscopy

Ratiometric Bioluminescent Indicator for Simple and Rapid Diagnosis of Bilirubin

Collaborators (11)

Yuki Hiruta

Yutaka Shindo

Kenta Temma

Tomoki Matsuda

Natsumi Hoshino

Kiwamu Takemoto

Yasuhiro Kamei

Takashi Kanadome

Kei-ichi Okazaki

Cong Quang Vu

Toshiki Kubo

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