Thiruma Arumugam

Professor

La Trobe University

Australia

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Thiruma Arumugam is a Professor at La Trobe University in Australia. His research encompasses areas such as metabolic diseases, vascular cognitive impairment, and the role of circadian rhythms in health and disease. Recent publications include studies on hypoxia-mediated CRIP2 activation, intermittent fasting, and the dynamics of bioenergetic pathways in the heart. His work contributes significantly to the understanding of the molecular mechanisms underlying various neurological and metabolic conditions.

Articles (18)

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2025

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2024

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2021

Collaborators (7)

Mitchell K. P. Lai

National University of Singapore (NUS)

SINGAPORE

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Vardan T. Karamyan

Texas Tech University Health Sciences Center

UNITED STATES

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Dong-Gyu Jo

Professor

Sungkyunkwan University

SOUTH KOREA

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M Prakash Hande

Assistant Dean, Safety and Research Facilities Management

National University of Singapore

SINGAPORE

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Lina Lim

Associate Professor

National University of Singapore (NUS)

SINGAPORE

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Asfa Alli-Shaik

International Institute of Molecular and Cell Biology

SINGAPORE

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Gavin Dawe

Associate Professor and Head of Department

National University of Singapore

SINGAPORE

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Thiruma Arumugam

Research Interests

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About

Articles (18)

Hypoxia-mediated CRIP2 activation via NICD1 translocation regulates glycolysis and cell death

Intermittent Metabolic Switching and Vascular Cognitive Impairment.

Circadian-Dependent Intermittent Fasting Influences Ischemic Tolerance and Dendritic Spine Remodeling

Hope for vascular cognitive impairment: Ac-YVAD-cmk as a novel treatment against white matter rarefaction

Role of Mitogen-Activated Protein (MAP) Kinase Pathways in Metabolic Diseases

Multiomics analyses reveal dynamic bioenergetic pathways and functional remodeling of the heart during intermittent fasting

Multiomics analyses reveal dynamic bioenergetic pathways and functional remodeling of the heart during intermittent fasting

The E3 ubiquitin ligase NEDD4 regulates chemoresistance to 5-fluorouracil in colorectal cancer cells by altering JNK signalling

Breast cancer metastasis to brain results in recruitment and activation of microglia through annexin-A1/formyl peptide receptor signaling

Time-restricted feeding modulates the DNA methylation landscape, attenuates hallmark neuropathology and cognitive impairment in a mouse model of vascular dementia.

The role of inflammasomes in vascular cognitive impairment

Effects of dietary interventions on telomere dynamics

Integrative epigenomic and transcriptomic analyses reveal metabolic switching by intermittent fasting in brain

Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment

Physiology and pharmacology of amyloid precursor protein

Intermittent fasting attenuates inflammasome-associated apoptotic and pyroptotic death in the brain following chronic hypoperfusion

Delayed atomoxetine or fluoxetine treatment coupled with limited voluntary running promotes motor recovery in mice after ischemic stroke.

AIM2 inflammasome mediates apoptotic and pyroptotic death in the cerebellum following chronic hypoperfusion

Collaborators (7)

Mitchell K. P. Lai

Vardan T. Karamyan

Dong-Gyu Jo

M Prakash Hande

Lina Lim

Asfa Alli-Shaik

Gavin Dawe

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