Thomas Stockner

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Assoc. Prof.

Medical University of Vienna

Austria

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Recent Grants

Grant: Close

NEUROtransmitter TRANSporters: from single molecules to human pathologies

Open Date: 2020-02-01

Close Date: 2024-01-01

Grant: Close

Energy coupling in the serotonin transporter

Open Date: 2019-02-01

Close Date: 2022-01-31

Grant: Close

Understanding Movements and Mechanism in Molecular Machines

Open Date: 2014-08-01

Close Date: 2018-09-01

Grant: Close

Transport cycle of the ABC transporter ABCB1

Open Date: 2011-05-01

Close Date: 2015-05-31

Grant: Close

Transmembrane Transporters in Health and Disease

Open Date:

Close Date:

Articles (14)

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2021

Collaborators (9)

Michael Freissmuth

AUSTRIA

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Florian Koban

Medical University of Vienna

AUSTRIA

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Deborah Rudin

Postdoc, Head Profiling

University Hospital Basel

SWITZERLAND

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Mina Aleksanyan

Max Planck Institute of Colloids and Interfaces

GERMANY

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Isabella Burger

Universität Wien

AUSTRIA

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Jae-Won Yang

Medical University of Vienna

AUSTRIA

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Dino Luethi

Research Associate & Lecturer

University Hospital Basel

SWITZERLAND

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Volodymyr Korkhov

ETH Zürich

SWITZERLAND

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Klaus Groschner

Professor

Medical University of Graz

AUSTRIA

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Thomas Stockner

Research Interests

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Recent Grants

Articles (14)

PIP2 modulates TRPC3 activity via TRP helix and S4-S5 linker

Free energy profile of the substrate‐induced occlusion of the human serotonin transporter

Probing binding and occlusion of substrate in the human creatine transporter‐1 by computation and mutagenesis

Nucleotide binding is the critical regulator of ABCG2 conformational transitions

YASARA Model–Interactive Molecular Modeling from Two Dimensions to Virtual Realities

(2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice

Phosphatidylinositol 4,5-bisphosphate (PIP2) facilitates norepinephrine transporter dimerization and modulates substrate efflux

Structural basis of organic cation transporter-3 inhibition

Diacylglycerols interact with the L2 lipidation site in TRPC3 to induce a sensitized channel state

Exploring TRPC3 Interaction with Cholesterol through Coarse-Grained Molecular Dynamics Simulations

Characterization of DAG Binding to TRPC Channels by Target-Dependent cis–trans Isomerization of OptoDArG

Occlusion of the human serotonin transporter is mediated by serotonin-induced conformational changes in the bundle domain

Sodium Binding Stabilizes the Outward-Open State of SERT by Limiting Bundle Domain Motions

Thermal unfolding of the human serotonin transporter: differential effect by stabilizing and destabilizing mutations and cholesterol on thermodynamic and kinetic stability

Collaborators (9)

Michael Freissmuth

Florian Koban

Deborah Rudin

Mina Aleksanyan

Isabella Burger

Jae-Won Yang

Dino Luethi

Volodymyr Korkhov

Klaus Groschner

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