Thorsten Lehr

Professor Clinical Pharmacy

Saarland University

Germany

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Professor Thorsten Lehr is a faculty member in Clinical Pharmacy at Saarland University, Germany. His research focuses on pharmacokinetics, particularly in developing physiologically based models for drug-drug interaction predictions and optimizing cancer therapy through precision dosing. Additionally, he investigates public health topics, including adolescent COVID-19 vaccination and the impact of the pandemic on internet use among adolescents.

Articles (18)

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2025

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2022

Collaborators (7)

Robert Dallmann

Associate Professor

University of Warwick

UNITED KINGDOM

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Johanna Weiss

University Hospital Heidelberg

GERMANY

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Uwe Fuhr

University of Cologne, Faculty of Medicine and University Hospital Cologne

GERMANY

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Folke Brinkmann

GERMANY

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Henk-Jan Guchelaar

Leiden University Medical Center

NETHERLANDS

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Jens Peter Klussmann

Professor and Chairman

GERMANY

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Walter E. Haefeli

GERMANY

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Thorsten Lehr

Research Interests

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About

Articles (18)

Development and Verification of a Physiologically Based Pharmacokinetic Model of Furmonertinib and Its Main Metabolite for Drug–Drug Interaction Predictions

Personalized Chronomodulated 5‐Fluorouracil Treatment: A Physiologically‐Based Pharmacokinetic Precision Dosing Approach for Optimizing Cancer Therapy

A physiologically‐based pharmacokinetic precision dosing approach to manage dasatinib drug–drug interactions

Physiologically based pharmacokinetic modeling of imatinib and N‐desmethyl imatinib for drug–drug interaction predictions

Big Epidemiology: The Birth, Life, Death, and Resurgence of Diseases on a Global Timescale

Physiologically Based Pharmacokinetic Modeling of Bergamottin and 6,7‐Dihydroxybergamottin to Describe CYP3A4 Mediated Grapefruit‐Drug Interactions

A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug–Drug Interaction Perpetrators

Significant impact of time-of-day variation on metformin pharmacokinetics

Motivations for Adolescent COVID-19 Vaccination: A Comparative Study of Adolescent and Caregiver Perspectives in Germany

Pharmacometric Modeling of the Impact of Azelastine Nasal Spray on SARS-CoV-2 Viral Load and Related Symptoms in COVID-19 Patients

Problematic Internet Use among Adolescents 18 Months after the Onset of the COVID-19 Pandemic

A Physiologically Based Pharmacokinetic and Pharmacodynamic Model of the CYP3A4 Substrate Felodipine for Drug–Drug Interaction Modeling

Mental Health and Health-Related Quality of Life in German Adolescents after the Third Wave of the COVID-19 Pandemic

Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug–Drug–Gene Interaction Predictions

A Novel Approach for Quantifying the Pharmacological Activity of T-Cell Engagers Utilizing In Vitro Time Course Experiments and Streamlined Data Analysis

Does the circulating ketoconazole metabolite N-deacetyl ketoconazole contribute to the drug-drug interaction potential of the parent compound?

Human papillomavirus vaccination of girls in the German model region Saarland: Insurance data-based analysis and identification of starting points for improving vaccination rates

In Vitro–In Silico Modeling of Caffeine and Diclofenac Permeation in Static and Fluidic Systems with a 16HBE Lung Cell Barrier

Collaborators (7)

Robert Dallmann

Johanna Weiss

Uwe Fuhr

Folke Brinkmann

Henk-Jan Guchelaar

Jens Peter Klussmann

Walter E. Haefeli

Make your next move.

Thorsten Lehr

Research Interests

Explore related searches

Contact this professor

About

Articles (18)

Development and Verification of a Physiologically Based Pharmacokinetic Model of Furmonertinib and Its Main Metabolite for Drug–Drug Interaction Predictions

Personalized Chronomodulated 5‐Fluorouracil Treatment: A Physiologically‐Based Pharmacokinetic Precision Dosing Approach for Optimizing Cancer Therapy

A physiologically‐based pharmacokinetic precision dosing approach to manage dasatinib drug–drug interactions

Physiologically based pharmacokinetic modeling of imatinib and N‐desmethyl imatinib for drug–drug interaction predictions

Big Epidemiology: The Birth, Life, Death, and Resurgence of Diseases on a Global Timescale

Physiologically Based Pharmacokinetic Modeling of Bergamottin and 6,7‐Dihydroxybergamottin to Describe CYP3A4 Mediated Grapefruit‐Drug Interactions

A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug–Drug Interaction Perpetrators

Significant impact of time-of-day variation on metformin pharmacokinetics

Motivations for Adolescent COVID-19 Vaccination: A Comparative Study of Adolescent and Caregiver Perspectives in Germany

Pharmacometric Modeling of the Impact of Azelastine Nasal Spray on SARS-CoV-2 Viral Load and Related Symptoms in COVID-19 Patients

Problematic Internet Use among Adolescents 18 Months after the Onset of the COVID-19 Pandemic

A Physiologically Based Pharmacokinetic and Pharmacodynamic Model of the CYP3A4 Substrate Felodipine for Drug–Drug Interaction Modeling

Mental Health and Health-Related Quality of Life in German Adolescents after the Third Wave of the COVID-19 Pandemic

Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug&ndash;Drug&ndash;Gene Interaction Predictions

A Novel Approach for Quantifying the Pharmacological Activity of T-Cell Engagers Utilizing In Vitro Time Course Experiments and Streamlined Data Analysis

Does the circulating ketoconazole metabolite N-deacetyl ketoconazole contribute to the drug-drug interaction potential of the parent compound?

Human papillomavirus vaccination of girls in the German model region Saarland: Insurance data-based analysis and identification of starting points for improving vaccination rates

In Vitro–In Silico Modeling of Caffeine and Diclofenac Permeation in Static and Fluidic Systems with a 16HBE Lung Cell Barrier

Collaborators (7)

Robert Dallmann

Johanna Weiss

Uwe Fuhr

Folke Brinkmann

Henk-Jan Guchelaar

Jens Peter Klussmann

Walter E. Haefeli

Make your next move.

Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug–Drug–Gene Interaction Predictions