Henk-Jan Guchelaar

Leiden University Medical Center

Netherlands

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Articles (21)

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2025

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2021

Collaborators (18)

Marieke Coenen

Associate Professor Pharmacogenetics

Erasmus MC

NETHERLANDS

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Segun Fatumo

Associate Professor

London School of Hygiene & Tropical Medicine

UNITED KINGDOM

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Apolonia Novillo

Universidad Complutense de Madrid

SPAIN

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Dirk Jan A. R. Moes

Leiden University Medical Center

NETHERLANDS

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Manuel Corpas

Lecturer in Genomics

University of Westminster

UNITED KINGDOM

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Kirsten J. M. Schimmel

NETHERLANDS

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Michel M. van den Heuvel

Radboud University Medical Center

NETHERLANDS

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Thorsten Lehr

Professor Clinical Pharmacy

Saarland University

GERMANY

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Brenda de Winter

Hospital Pharmacist - Assistant Professor

Erasmus University Medical Center

NETHERLANDS

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Shivashankar Nagaraj

Queensland University of Technology

AUSTRALIA

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J.G.C. van Hasselt

Associate professor

Leiden University

NETHERLANDS

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Ana Fernández-Santander

Ph D, Professor / Catedrática de genética

Universidad Autónoma de Madrid

SPAIN

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Hans Gelderblom

Prof.dr.

Leiden University Medical Center

NETHERLANDS

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Egbert Smit

Leiden University Medical Center

NETHERLANDS

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Ellen H. W. Kapiteijn

Leiden University Medical Center

NETHERLANDS

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Teun van Gelder

Professor in Drug Discovery & Development

Leiden University Medical Center

NETHERLANDS

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Jesse Swen

Full professor of clinical pharmacy, in particular translational pharmacogenetics

Leiden University Medical Center

NETHERLANDS

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Espen Molden

NORWAY

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Henk-Jan Guchelaar

Research Interests

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Articles (21)

Pharmacogenetic Implementation Studies—Lessons Learned From the PREPARE Study

Improved Prediction of CYP2D6 Catalyzed Drug Metabolism by Taking Variant Substrate Specificities and Novel Polymorphic Haplotypes into Account

Reporting Adverse Drug Events: A Comparison of an Online Patient Tool Versus Telephone-Based Monitoring in Community Pharmacy Patients in the Netherlands

Model-Informed Development of a Cost-Saving Dosing Regimen for Sacituzumab Govitecan

Quantitative modeling of tumor dynamics and development of drug resistance in non‐small cell lung cancer patients treated with erlotinib

Mapping the Pharmacogenetic Landscape in a Ugandan Population: Implications for Personalized Medicine in an Underrepresented Population

Nonlinear Mixed‐Effects Model of Z‐Endoxifen Concentrations in Tamoxifen‐Treated Patients from the CEPAM Cohort

A Genome‐Wide Association Study of Endoxifen Serum Concentrations and Adjuvant Tamoxifen Efficacy in Early‐Stage Breast Cancer Patients

Inflammation altered correlation between CYP2C19 genotype and CYP2C19 activity in patients receiving voriconazole

Personalized Chronomodulated 5‐Fluorouracil Treatment: A Physiologically‐Based Pharmacokinetic Precision Dosing Approach for Optimizing Cancer Therapy

A Nomogram to Predict Severe Toxicity in DPYD Wild‐Type Patients Treated With Capecitabine‐Based Anticancer Regimens

UGT1A1 genotype-guided dosing of irinotecan: time to prioritize patient safety

Development and Bioequivalence of 3D‐Printed Medication at the Point‐of‐Care: Bridging the Gap Toward Personalized Medicine

Response to “Plasma Uracil as a DPD Phenotyping Test: Pre‐analytical Handling Matters”

Reply to: Temporary Like Achilles: Pre‐emptive germline pharmacogenetic testing

Genome-Wide Analyses of Nephrotoxicity in Platinum-Treated Cancer Patients Identify Association with Genetic Variant in <i>RBMS3</i> and Acute Kidney Injury

Application of Electronic Health Record Text Mining: Real-World Tolerability, Safety, and Efficacy of Adjuvant Melanoma Treatments

Genome-Wide Meta-Analysis Identifies Variants in <i>DSCAM</i> and <i>PDLIM3</i> That Correlate with Efficacy Outcomes in Metastatic Renal Cell Carcinoma Patients Treated with Sunitinib

The Potential Application of Extracellular Vesicles from Liquid Biopsies for Determination of Pharmacogene Expression

3D Printing of Pediatric Medication: The End of Bad Tasting Oral Liquids?—A Scoping Review

Genotyping for HLA Risk Alleles to Prevent Drug Hypersensitivity Reactions: Impact Analysis

Collaborators (18)

Marieke Coenen

Segun Fatumo

Apolonia Novillo

Dirk Jan A. R. Moes

Manuel Corpas

Kirsten J. M. Schimmel

Michel M. van den Heuvel

Thorsten Lehr

Brenda de Winter

Shivashankar Nagaraj

J.G.C. van Hasselt

Ana Fernández-Santander

Hans Gelderblom

Egbert Smit

Ellen H. W. Kapiteijn

Teun van Gelder

Jesse Swen

Espen Molden

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