Tim Karl

Professor for Behavioural Neuroscience

Western Sydney University - Campbelltown Campus

Australia

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Tim Karl is a Professor for Behavioural Neuroscience at Western Sydney University - Campbelltown Campus, Australia. His research encompasses the effects of cannabidiol (CBD) on behavioral outcomes, neuroinflammation, and cognitive function in various animal models. Recent publications highlight the implications of CBD on conditions such as schizophrenia and Alzheimer's disease, as well as the influence of voluntary exercise on retinal degeneration.

Articles (20)

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Collaborators (18)

Yuanyuan Deng

Macquarie University

AUSTRALIA

Tim Karl

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Articles (20)

Persistent behavioural consequences of chronic adolescent cannabidiol (CBD) in a mouse model with increased susceptibility to Δ&lt;sup&gt;9&lt;/sup&gt;-tetrahydrocannabinol and schizophrenia.

Cannabidiol (CBD) facilitates cocaine extinction and ameliorates cocaine-induced changes to the gut microbiome in male C57BL/6JArc mice.

Voluntary exercise modulates pathways associated with amelioration of retinal degenerative diseases

Chronic interleukin-6 mediated neuroinflammation decreases anxiety, and impaires spatial memory in aged female mice.

Light phase does not affect operant sucrose self-administration in adult male C57BL/6JAbr mice.

Impaired extinction of operant cocaine in a genetic mouse model of schizophrenia risk.

Loss of LAMP5 interneurons drives neuronal network dysfunction in Alzheimer's disease

Cannabidiol (CBD) treatment improves spatial memory in 14-month-old female TAU58/2 transgenic mice

The effects of preventative cannabidiol in a male neuregulin 1 mouse model of schizophrenia

Effect of long-term cannabidiol on learning and anxiety in a female Alzheimer's disease mouse model.

Therapeutic properties of multi-cannabinoid treatment strategies for Alzheimer's disease.

The behavioural phenotype of 14-month-old female TAU58/2 transgenic mice

Treatment of microglia with Anti-PrP monoclonal antibodies induces neuronal apoptosis <i>in vitro</i>.

CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1<sup>G93A</sup> mice with a C57BL/6 background.

Cross-Linking Cellular Prion Protein Induces Neuronal Type 2-Like Hypersensitivity.

Spatial Memory and Microglia Activation in a Mouse Model of Chronic Neuroinflammation and the Anti-inflammatory Effects of Apigenin.

Characterisation of the Mouse Cerebellar Proteome in the GFAP-IL6 Model of Chronic Neuroinflammation.

Behavioural effects of cage systems on the G93ASuperoxide Dismutase 1 transgenic mouse model for amyotrophic lateral sclerosis

Effects of handling on the behavioural phenotype of the neuregulin 1 type III transgenic mouse model for schizophrenia

Mouse model of Alzheimer's disease demonstrates differential effects of early disease pathology on various brain regions.

Collaborators (18)

Yuanyuan Deng

Samara Walpole

Yazi Ke

Arne Ittner

Mian Bi

Magdalena Przybyla

Gabriella Chan

Riccardo Natoli

Chun Guang Li

Lars Ittner

Annika van Hummel

Veer Gupta

Erika Gyengesi

Fabien Delerue

Lezanne Ooi

Justin Yerbury

Meena Mikhael

yvette wooff

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Persistent behavioural consequences of chronic adolescent cannabidiol (CBD) in a mouse model with increased susceptibility to Δ<sup>9</sup>-tetrahydrocannabinol and schizophrenia.