Tim R. Blower

Professor

University of Durham

United Kingdom

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Articles (13)

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2024

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2022

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2021

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2020

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2020

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2020

Collaborators (9)

Roland Barriot

Lecturer

FRANCE

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Martin Cann

Reader

University of Durham

UNITED KINGDOM

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Peter Redder

Professor

Université de Toulouse

FRANCE

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Bert van den Berg

Professor of Membrane Protein Structural Biology

Newcastle University

UNITED KINGDOM

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Caroline Austin

Professor

Newcastle University

UNITED KINGDOM

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Claude Gutierrez

Professeur

Université Paul Sabatier

FRANCE

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David Hodgson

Professor

University of Durham

UNITED KINGDOM

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Jan Verlet

Professor

University of Durham

UNITED KINGDOM

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Jay Hinton

Professor of Microbial Pathogenesis

University of Liverpool

UNITED KINGDOM

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Tim R. Blower

Research Interests

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Articles (13)

Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins

Toxin release by conditional remodelling of ParDE1 from Mycobacterium tuberculosis leads to gyrase inhibition

Using energy to go downhill—a genoprotective role for ATPase activity in DNA topoisomerase II

MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding

Naturally mutagenic sequence diversity in a human type II topoisomerase

Allophycocyanin A is a carbon dioxide receptor in the cyanobacterial phycobilisome

A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193

A widespread family of WYL-domain transcriptional regulators co-localizes with diverse phage defence systems and islands

Crystal structure of the BREX phage defence protein BrxA

The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses.

A nucleotidyltransferase toxin inhibits growth of Mycobacterium tuberculosis through inactivation of tRNA acceptor stems

Antitoxin autoregulation of M. tuberculosis toxin-antitoxin expression through negative cooperativity arising from multiple inverted repeat sequences

Anticancer Ruthenium Complexes with HDAC Isoform Selectivity

Collaborators (9)

Roland Barriot

Martin Cann

Peter Redder

Bert van den Berg

Caroline Austin

Claude Gutierrez

David Hodgson

Jan Verlet

Jay Hinton

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