Timothy Osborne

Professor

Johns Hopkins All Children's Hospital

United States

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Timothy Osborne is a Professor at Johns Hopkins All Children's Hospital in the United States. His research primarily focuses on the transcriptional regulation of adipose tissue, mechanotransduction, and the roles of various lipid regulatory proteins in metabolic processes. Recent articles encompass topics such as adipocyte function, immune responses, and the impact of epigenetics on fat distribution.

Articles (12)

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2021

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2021

Collaborators (5)

Padmanabhan Paranji Pattabiraman

UNITED STATES

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Yajaira Suárez

Professor

Yale University School of Medicine

UNITED STATES

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Sang-Ik Park

SOUTH KOREA

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Peter Espenshade

Professor

Johns Hopkins University

UNITED STATES

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Carlos Fernández-Hernando

Yale University School of Medicine

UNITED STATES

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Timothy Osborne

Research Interests

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Articles (12)

SCAP deficiency facilitates obesity and insulin resistance through shifting adipose tissue macrophage polarization

SREBP signaling is essential for effective B cell responses

Identification of the novel role of sterol regulatory element binding proteins (SREBPs) in mechanotransduction and intraocular pressure regulation

Transcriptional Control of Subcutaneous Adipose Tissue by the Transcription Factor CTCF Modulates Heterogeneity in Fat Distribution in Women

Lipid balance must be just right to prevent development of severe liver damage

Epigenetic and environmental regulation of adipocyte function

MYPT1-PP1 beta phosphatase negatively regulates both chromatin landscape and co-activator recruitment for beige adipogenesis

Therapeutic strategy targeting host lipolysis limits infection by SARS-CoV-2 and influenza A virus

Transcriptional and DNA Methylation Signatures of Subcutaneous Adipose Tissue and Adipose-Derived Stem Cells in PCOS Women

Unique role for lncRNA HOTAIR in defining depot-specific gene expression patterns in human adipose-derived stem cells

Deficiency of histone lysine methyltransferase SETDB2 in hematopoietic cells promotes vascular inflammation and accelerates atherosclerosis

Deficiency of histone lysine methyltransferase SETDB2 in hematopoietic cells promotes vascular inflammation and accelerates atherosclerosis

Collaborators (5)

Padmanabhan Paranji Pattabiraman

Yajaira Suárez

Sang-Ik Park

Peter Espenshade

Carlos Fernández-Hernando

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