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Tomasz Śliwiński

Professor

Medical University of Lodz

Poland

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Research Interests

Pharmacology

90%

Cell Biology

50%

Cancer Biology

40%

Phytochemical

40%

In Vitro Studies

30%

Inflammatory Biology

20%

Antioxidant Therapy

20%

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Recent Grants

Grant: Close

Medycyna spersonalizowana leczenia guzów litych wykorzystująca terapię celowaną w mechanizmy naprawy DNA, w oparciu o zjawisko syntetycznej letalności

Open Date: 2017-04-13

Close Date: 2021-04-12

Grant: Close

Rola procesu zapalnego, stresu oksydacyjnego i nitryzacyjnego, szlaku katabolitów tryptofanu oraz naprawy DNA przez wycinanie zasad w depresji i w mechanizmie działania leków przeciwdepresyjnych, w przedklinicznych i klinicznych badaniach in vitro i in vivo.

Open Date: 2016-07-08

Close Date: 2019-07-07

Grant: Close

Białka naprawy pęknięć dwuniciowych DNA jako cele dla spersonalizowanej terapii przeciwnowotworowej opartej na syntetycznej letalności

Open Date: 2013-07-02

Close Date: 2017-01-01

Grant: Close

Aspekty funkcjonalne, epigenetyczne oraz genetyczne szlaku naprawy DNA przez wycinanie zasad azotowych w chorobie Alzheimera

Open Date: 2013-02-12

Close Date: 2016-02-11

Tomasz Śliwiński

Professor

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Recent Grants

Articles15

Biological Properties of Extracts Obtained from In Vitro Culture of Plectranthus scutellarioides in a Cell Model

Polθ Inhibitor (ART558) Demonstrates a Synthetic Lethal Effect with PARP and RAD52 Inhibitors in Glioblastoma Cells

Histone Deacetylases (HDAC) Inhibitor—Valproic Acid Sensitizes Human Melanoma Cells to Dacarbazine and PARP Inhibitor

Chitosan Nanoparticles-Preparation, Characterization and Their Combination with Ginkgo biloba Extract in Preliminary In Vitro Studies

New Data on Anti-Inflammatory and Wound Healing Potential of Transgenic Senna obtusifolia Hairy Roots: In Vitro Studies

Leonotis nepetifolia Transformed Root Extract Reduces Pro-Inflammatory Cytokines and Promotes Tissue Repair In Vitro

Class I HDAC Inhibition Leads to a Downregulation of FANCD2 and RAD51, and the Eradication of Glioblastoma Cells

Mitochondrial Damage Induced by T-2 Mycotoxin on Human Skin—Fibroblast Hs68 Cell Line

Enhanced Natural Strength: Lamiaceae Essential Oils and Nanotechnology in In Vitro and In Vivo Medical Research

DNA Damage Induced by T-2 Mycotoxin in Human Skin Fibroblast Cell Line—Hs68

Single-Nucleotide Polymorphisms in Genes Maintaining the Stability of Mitochondrial DNA Affect the Occurrence, Onset, Severity and Treatment of Major Depressive Disorder

An Evaluation of the Novel Biological Properties of Diterpenes Isolated from Plectranthus ornatus Codd. In Vitro and In Silico

Polθ Inhibition: An Anticancer Therapy for HR-Deficient Tumours

Agomelatine Changed the Expression and Methylation Status of Inflammatory Genes in Blood and Brain Structures of Male Wistar Rats after Chronic Mild Stress Procedure

Synthetic Lethality Targeting Polθ

Collaborators18

Przemysław Sitarek

Joanna Sikora

Mariusz Papp

Piotr Czarny

Paulina Wigner

Tomasz Kowalczyk

Joanna Wieczfinska

Maciej Radek

Marcin Niemcewicz

Małgorzata Gałecka

MAREK WIECZOREK

Janusz Szemraj

Malgorzata Czyz

Michal Bijak

Piotr Gałecki

Rafał Pawliczak

Ewelina Synowiec

Anna Merecz-Sadowska

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