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Tomoyoshi Nozaki

Professor

Graduate School of Medicine, The University of Tokyo

Japan

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Research Interests

Biochemistry

50%

Cell Biology

40%

Eukaryotic Biology

40%

Host-parasite Interaction

30%

Mitochondrial Biology

20%

Chemical Biology

20%

Drug Development

20%

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Articles20

Draft genome of the marine Entamoeba species reveals reduction in the gene family repertoire associated with pathogenicity and lateral gene transfer for adaptation to the marine environment

Article Link

Year:

2025

Metronidazole induces prostaglandin E2 formation via arachidonic acid production in protozoan parasite Giardia lamblia

Article Link

Year:

2025

A New Multiplex PCR Assay Reveals the Occurrence of E. bangladeshi alongside E. histolytica and E. moshkovskii in Eastern India

Article Link

Year:

2024

A rapid economical multiplex PCR-RFLP method for molecular detection and genotyping of Giardia duodenalis clinical isolates

Article Link

Year:

2024

Andrographolide induced cytotoxicity and cell cycle arrest in Giardia trophozoites

Article Link

Year:

2024

Antimalarial activity of borrelidin and fumagilin in Plasmodium berghei-infected mice

Article Link

Year:

2024

EhRacM differentially regulates macropinocytosis and motility in the enteric protozoan parasite Entamoeba histolytica

Article Link

Year:

2024

EhRacM differentially regulates macropinocytosis and motility in the enteric protozoan parasiteEntamoeba histolytica

Article Link

Year:

2024

Evidence of γ-secretase complex involved in the regulation of intramembrane proteolysis in Entamoeba histolytica

Article Link

Year:

2024

Exploring Indonesian actinomycete extracts for anti-tubercular compounds: Integrating inhibition assessment, genomic analysis, and prediction of its target by molecular docking

Article Link

Year:

2024

Non-Vesicular Lipid Transport Machinery in Leishmania donovani: Functional Implications in Host-Parasite Interaction

Article Link

Year:

2023

Attenuation of In Vitro and In Vivo Virulence Is Associated with Repression of Gene Expression of AIG1 Gene in Entamoeba histolytica

Article Link

Year:

2023

Nornidulin, A New Inhibitor of Plasmodium falciparum Malate: Quinone Oxidoreductase (PfMQO) from Indonesian Aspergillus sp. BioMCC f.T.8501

Article Link

Year:

2023

Molecular Dissection of Phagocytosis by Proteomic Analysis in Entamoeba histolytica

Article Link

Year:

2023

Siccanin Is a Dual-Target Inhibitor of Plasmodium falciparum Mitochondrial Complex II and Complex III

Article Link

Year:

2022

Transfer RNA-Derived Small RNAs in the Pathogenesis of Parasitic Protozoa

Article Link

Year:

2022

Biochemical Studies of Mitochondrial Malate: Quinone Oxidoreductase from Toxoplasma gondii

Article Link

Year:

2021

Identification of 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase

Article Link

Year:

2021

Trogocytosis in Unicellular Eukaryotes

Article Link

Year:

2021

Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target

Article Link

Year:

2020

Collaborators6

Daniel Ken INAOKA

Associate Professor

Nagasaki University

JAPAN

Herbert Santos

Assistant Professor

University of Tokyo

JAPAN

Yuichi Matsuo

Assistant Professor

Kumamoto University

JAPAN

Fuyuki Tokumasu

Professor

Gunma University

JAPAN

Takaya Sakura

Nagasaki University

JAPAN

Shinjiro Hamano

Nagasaki University

JAPAN

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Tomoyoshi Nozaki

Professor

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Research Interests

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Articles20

Draft genome of the marine Entamoeba species reveals reduction in the gene family repertoire associated with pathogenicity and lateral gene transfer for adaptation to the marine environment

Metronidazole induces prostaglandin E2 formation via arachidonic acid production in protozoan parasite Giardia lamblia

A New Multiplex PCR Assay Reveals the Occurrence of E. bangladeshi alongside E. histolytica and E. moshkovskii in Eastern India

A rapid economical multiplex PCR-RFLP method for molecular detection and genotyping of Giardia duodenalis clinical isolates

Andrographolide induced cytotoxicity and cell cycle arrest in Giardia trophozoites

Antimalarial activity of borrelidin and fumagilin in <i>Plasmodium berghei</i>-infected mice

EhRacM differentially regulates macropinocytosis and motility in the enteric protozoan parasite Entamoeba histolytica

EhRacM differentially regulates macropinocytosis and motility in the enteric protozoan parasite<i>Entamoeba histolytica</i>

Evidence of γ-secretase complex involved in the regulation of intramembrane proteolysis in Entamoeba histolytica

Exploring Indonesian actinomycete extracts for anti-tubercular compounds: Integrating inhibition assessment, genomic analysis, and prediction of its target by molecular docking

Non-Vesicular Lipid Transport Machinery in <i>Leishmania donovani</i>: Functional Implications in Host-Parasite Interaction

Attenuation of In Vitro and In Vivo Virulence Is Associated with Repression of Gene Expression of AIG1 Gene in <i>Entamoeba histolytica</i>

Nornidulin, A New Inhibitor of <i>Plasmodium falciparum</i> Malate: Quinone Oxidoreductase (<i>Pf</i>MQO) from Indonesian <i>Aspergillus</i> sp. BioMCC f.T.8501

Molecular Dissection of Phagocytosis by Proteomic Analysis in <i>Entamoeba histolytica</i>

Siccanin Is a Dual-Target Inhibitor of <i>Plasmodium falciparum</i> Mitochondrial Complex II and Complex III

Transfer RNA-Derived Small RNAs in the Pathogenesis of Parasitic Protozoa

Biochemical Studies of Mitochondrial Malate: Quinone Oxidoreductase from Toxoplasma gondii

Identification of 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase

Trogocytosis in Unicellular Eukaryotes

Structural and Biochemical Features of <i>Eimeria tenella</i> Dihydroorotate Dehydrogenase, a Potential Drug Target

Collaborators6

Daniel Ken INAOKA

Herbert Santos

Yuichi Matsuo

Fuyuki Tokumasu

Takaya Sakura

Shinjiro Hamano

How do I reach out?

Tomoyoshi Nozaki

Professor

How do I reach out?

Contact this professor

Research Interests

Ask ApplyKite AI

Articles20

Draft genome of the marine Entamoeba species reveals reduction in the gene family repertoire associated with pathogenicity and lateral gene transfer for adaptation to the marine environment

Metronidazole induces prostaglandin E2 formation via arachidonic acid production in protozoan parasite Giardia lamblia

A New Multiplex PCR Assay Reveals the Occurrence of E. bangladeshi alongside E. histolytica and E. moshkovskii in Eastern India

A rapid economical multiplex PCR-RFLP method for molecular detection and genotyping of Giardia duodenalis clinical isolates

Andrographolide induced cytotoxicity and cell cycle arrest in Giardia trophozoites

Antimalarial activity of borrelidin and fumagilin in &lt;i&gt;Plasmodium berghei&lt;/i&gt;-infected mice

EhRacM differentially regulates macropinocytosis and motility in the enteric protozoan parasite Entamoeba histolytica

EhRacM differentially regulates macropinocytosis and motility in the enteric protozoan parasite&lt;i&gt;Entamoeba histolytica&lt;/i&gt;

Evidence of γ-secretase complex involved in the regulation of intramembrane proteolysis in Entamoeba histolytica

Exploring Indonesian actinomycete extracts for anti-tubercular compounds: Integrating inhibition assessment, genomic analysis, and prediction of its target by molecular docking

Non-Vesicular Lipid Transport Machinery in <i>Leishmania donovani</i>: Functional Implications in Host-Parasite Interaction

Attenuation of In Vitro and In Vivo Virulence Is Associated with Repression of Gene Expression of AIG1 Gene in <i>Entamoeba histolytica</i>

Nornidulin, A New Inhibitor of <i>Plasmodium falciparum</i> Malate: Quinone Oxidoreductase (<i>Pf</i>MQO) from Indonesian <i>Aspergillus</i> sp. BioMCC f.T.8501

Molecular Dissection of Phagocytosis by Proteomic Analysis in <i>Entamoeba histolytica</i>

Siccanin Is a Dual-Target Inhibitor of <i>Plasmodium falciparum</i> Mitochondrial Complex II and Complex III

Transfer RNA-Derived Small RNAs in the Pathogenesis of Parasitic Protozoa

Biochemical Studies of Mitochondrial Malate: Quinone Oxidoreductase from Toxoplasma gondii

Identification of 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase

Trogocytosis in Unicellular Eukaryotes

Structural and Biochemical Features of <i>Eimeria tenella</i> Dihydroorotate Dehydrogenase, a Potential Drug Target

Collaborators6

Daniel Ken INAOKA

Herbert Santos

Yuichi Matsuo

Fuyuki Tokumasu

Takaya Sakura

Shinjiro Hamano

How do I reach out?

Antimalarial activity of borrelidin and fumagilin in <i>Plasmodium berghei</i>-infected mice

EhRacM differentially regulates macropinocytosis and motility in the enteric protozoan parasite<i>Entamoeba histolytica</i>