Uwe MASKOS

Lab Chief

Institut Pasteur

France

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Uwe Maskos is a Lab Chief at Institut Pasteur in France. His research areas include the roles of nicotinic acetylcholine receptors in neurological disorders, the interaction between nicotine and neural circuits related to anxiety, and the implications of specific genetic mutations in alcohol use and psychiatric conditions. Recent publications highlight his work on neuronal dysfunction and the therapeutic potential of targeting nicotinic receptors in conditions such as bipolar disorder and schizophrenia.

Articles (10)

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2025

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2025

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2025

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2025

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2024

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2024

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2024

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2024

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2024

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2023

Collaborators (1)

Petra Scholze

Medical University of Vienna Center for Brain Research

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Uwe MASKOS

Research Interests

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Articles (10)

The alpha7 nicotinic acetylcholine receptor mediates network dysfunction in a mouse model of local amyloid pathology.

Nicotine engages a VTA-NAc feedback loop to inhibit amygdala-projecting dopamine neurons and induce anxiety-like behaviors.

The interpeduncular nucleus blunts the rewarding effect of nicotine.

Linking altered neuronal and synaptic properties to nicotinic receptor Alpha5 subunit gene dysfunction: a translational investigation in rat mPFC and human cortical layer 6

The human‐specific nicotinic receptor subunit CHRFAM7A reduces α7 receptor function in human induced pluripotent stem cells‐derived and transgenic mouse neurons

Distinct Chrna5 mutations link excessive alcohol use to types I/II vulnerability profiles and IPN GABAergic neurons.

Targeting high-affinity nicotinic receptors protects against the functional consequences of β-amyloid in mouse hippocampus.

B Cell-activating factor (BAFF): A promising trans-nosographic biomarker of inflammation and autoimmunity in bipolar disorder and schizophrenia.

Serum autoantibodies against α7-nicotinic receptors in subgroups of patients with bipolar disorder or schizophrenia: clinical features and link with peripheral inflammation.

Functional maturation of human iPSC-derived pyramidal neurons <i>in vivo</i> is dependent on proximity with the host tissue.

Collaborators (1)

Petra Scholze

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