Vaughn Cooper

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Professor

University of Pittsburgh

United States

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About

Vaughn Cooper is a Professor at the University of Pittsburgh in the United States. His research primarily focuses on microbiology, with recent articles exploring topics such as climate action in microbial communities, antibiotic resistance in Pseudomonas aeruginosa and Acinetobacter baumannii, and the dynamics of pathogens in cystic fibrosis. He actively engages with issues related to ecology, evolution, and biodiversity, contributing to discussions within the American Society for Microbiology.

Recent Grants

Grant: Close

Collaborative Proposal: Role of tRNA base modifications in genetic code accuracy and bacterial fitness

Open Date: 2018-08-01

Close Date: 2021-07-01

Grant: Close

Collaborative Proposal: Role of tRNA base modifications in genetic code accuracy and bacterial fitness

Open Date: 2018-08-01

Close Date: 2021-07-31

Grant: Close

Predicting the emergence of antibiotic resistance through multi-omics approaches and Immune System-surveillan

Open Date: 2016-03-10

Close Date: 2021-02-28

Grant: Close

Predicting the emergence of antibiotic resistance through multi-omics approaches and Immune System-surveillan

Open Date: 2016-03-01

Close Date: 2021-02-01

Grant: Close

Molecular mechanisms of adaptive diversity in Burkholderia biofilms

Open Date: 2015-01-01

Close Date: 2019-12-01

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2021

Collaborators (15)

Mark Davis

Howard Hughes Medical Institute

UNITED STATES

Vaughn Cooper

Research Interests

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About

Recent Grants

Articles (25)

Mutations leading to ceftolozane/tazobactam and imipenem/cilastatin/relebactam resistance during in vivo exposure to ceftazidime/avibactam in Pseudomonas aeruginosa

Microbes without borders: uniting societies for climate action

Microbes without borders: uniting societies for climate action

History shapes regulatory and evolutionary responses to tigecycline in two reference strains of Acinetobacter baumannii

Feeling abandoned but energized

Cystic fibrosis pathogens persist in the upper respiratory tract following initiation of elexacaftor/tezacaftor/ivacaftor therapy

Complete genome sequence of Vibrio parahaemolyticus ST36 strain MAVP-26, a clinical isolate from an oyster-borne human gastric infection

Erratum for Foxall et al., “ Inoviridae prophage and bacterial host dynamics during diversification, succession, and Atlantic invasion of Pacific-native Vibrio parahaemolyticus ”

Harnessing the Diversity of Burkholderia spp. Prophages for Therapeutic Potential

Streptococcus pneumoniae favors tolerance via metabolic adaptation over resistance to circumvent fluoroquinolones

Inoviridae prophage and bacterial host dynamics during diversification, succession, and Atlantic invasion of Pacific-native Vibrio parahaemolyticus

Confronting risks of mirror life

Perspectives on the future of ecology, evolution, and biodiversity from the Council on Microbial Sciences of the American Society for Microbiology

Adaptation to Overflow Metabolism by Mutations That Impair tRNA Modification in Experimentally Evolved Bacteria

Draft genomes of seven isolates from Danish wastewater facilities belonging to Pseudomonas, Bacillus, Pseudochrobactrum, Brevundimonas, and Pandoraea

The contribution of DNA repair pathways to Staphylococcus aureus fitness and fidelity during nitric oxide stress

Novel Requirement for Staphylococcal Cell Wall-Anchored Protein SasD in Pulmonary Infection

Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania

Immunosuppression broadens evolutionary pathways to drug resistance and treatment failure during Acinetobacter baumannii pneumonia in mice

The Nutritional Environment Is Sufficient To Select Coexisting Biofilm and Quorum Sensing Mutants of Pseudomonas aeruginosa

The nutritional environment is sufficient to select coexisting biofilm and quorum-sensing mutants of Pseudomonas aeruginosa

Evolved resistance to a novel cationic peptide antibiotic requires high mutation supply

Polygenic Adaptation and Clonal Interference Enable Sustained Diversity in Experimental Pseudomonas aeruginosa Populations

Evolutionary Divergence of the Wsp Signal Transduction Systems in Beta- and Gammaproteobacteria

Precise measurement of the fitness effects of spontaneous mutations by droplet digital PCR in Burkholderia cenocepacia

Collaborators (15)

Mark Davis

george church

Jay T. Lennon

David A. Relman

Joseph Nesme

Way Sung

Daria Van Tyne

Katrine Whiteson

James Andrew Smith

Cheryl Whistler

Jack W. Szostak

Peter R. Girguis

Edward Geisinger

Elena Litchman

John Glass

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