Wei Guo

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University of Wisconsin-Madison

United States

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Recent Grants

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Targeting titin for the treatment of Heart Failure with Preserved Ejection Fraction (HFpEF)

Open Date: 2023-07-01

Close Date: 2026-06-30

Grant: Close

Cytoplasmic trafficking of titin mRNA binding protein 20 in heart failure progression

Open Date: 2019-07-01

Close Date: 2022-06-30

Articles (16)

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2022

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2022

Label-free quantitative proteomics identifies molecular correlates of dilated cardiomyopathy in rats lacking the muscle-specific splicing factor Rbm20 .

Year:

2022

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2022

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2022

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2022

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2021

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2021

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2020

Collaborators (5)

Francesca Briganti

Assistant Professor

UCSD

UNITED STATES

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Mei Methawasin

Research Assistant Professor

University of Arizona

UNITED STATES

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Michael Gotthardt

W3 (Full) Professor

Max Delbrück Centrum für Molekulare Medizin Berlin Buch

GERMANY

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Camila U. Braz

Assistant Professor

UNITED STATES

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Timothy Kamp

Professor

University of Wisconsin-Madison

UNITED STATES

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Wei Guo

Research Interests

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Recent Grants

Articles (16)

Mechanisms of RBM20 Cardiomyopathy: Insights From Model Systems

Divergent Regulatory Roles of Transcriptional Variants of the Chicken LDB3 Gene in Muscle Shaping

Titin: roles in cardiac function and diseases

Disruption of the nuclear localization signal in RBM20 is causative in dilated cardiomyopathy

A look under the hood of genomic-estimated breed compositions for brangus cattle: What have we learned?

High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms

Top-down proteomics of myosin light chain isoforms define chamber-specific expression in the human heart

RBM20 phosphorylation and its role in nucleocytoplasmic transport and cardiac pathogenesis.

RBM20<sup>S639G</sup> mutation is a high genetic risk factor for premature death through RNA-protein condensates.

<i>Rbm20</i> ablation is associated with changes in the expression of titin-interacting and metabolic proteins

SR Protein Kinases Regulate the Splicing of Cardiomyopathy-Relevant Genes via Phosphorylation of the RSRSP Stretch in RBM20

Rbm20 ablation is associated with changes in the expression of titin-interacting and metabolic proteins

Maternal Overnutrition During Gestation in Sheep Alters Autophagy Associated Pathways in Offspring Heart

The ryanodine receptor stabilizer S107 ameliorates contractility of adult Rbm20 knockout rat cardiomyocytes

Author Correction: Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs

Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs

Collaborators (5)

Francesca Briganti

Mei Methawasin

Michael Gotthardt

Camila U. Braz

Timothy Kamp

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