Weixi Gu

University of Queensland

Australia

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Articles (12)

Year:

2024

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2024

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2024

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2023

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Year:

2021

Collaborators (6)

Laura Pacoste

Stockholm University

SWEDEN

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Thomas Ve

Griffith University

AUSTRALIA

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Hongyi Xu

SWEDEN

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Michael Landsberg

Senior Lecturer

University of Queensland

AUSTRALIA

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Bostjan Kobe

Professor

University of Queensland

AUSTRALIA

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Alpesh MALDE

Griffith University

AUSTRALIA

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Weixi Gu

Research Interests

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Articles (12)

Microcrystal electron diffraction structure of Toll-like receptor 2 TIR-domain-nucleated MyD88 TIR-domain higher-order assembly

Structural characterization of TIR-domain signalosomes through a combination of structural biology approaches

Structural characterization of macro domain-containing Thoeris antiphage defense systems.

SARM1-Dependent Axon Degeneration: Nucleotide Signaling, Neurodegenerative Disorders, Toxicity, and Therapeutic Opportunities

Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling

Crystal structure of the Toll/interleukin‐1 receptor (TIR) domain of IL‐1R10 provides structural insights into TIR domain signalling

Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1

Structural Evolution of TIR-Domain Signalosomes

Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection

Crystal structure determination of the armadillo repeat domain of Drosophila SARM1 using MIRAS phasing

A Novel NAD Signaling Mechanism in Axon Degeneration and its Relationship to Innate Immunity

SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration

Collaborators (6)

Laura Pacoste

Thomas Ve

Hongyi Xu

Michael Landsberg

Bostjan Kobe

Alpesh MALDE

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