Wenpeng Liu

Assistant Professor

University of Virginia

United States

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About

Wenpeng Liu is an Assistant Professor at the University of Virginia, USA. His research focuses on DNA replication and the mechanisms of genome stability, particularly examining the roles of FANCD2 and RAD51 in DNA repair processes. Recent publications include studies on replication fork dynamics and the impact of stress on DNA replication.

Articles (5)

Year:

2023

Year:

2023

Year:

2023

Year:

2021

Year:

2020

Collaborators (4)

Binghui Shen

Professor and Chair

Beckman Research Institute, City of Hope

UNITED STATES

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David Cortez

Professor

Vanderbilt University

UNITED STATES

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James Dewar

Assistant-Professor

Vanderbilt University School of Medicine

UNITED STATES

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Masato Kanemaki

Professor (Interlocking faculty member)

University of Tokyo

JAPAN

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Wenpeng Liu

Research Interests

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Articles (5)

FANCD2 and RAD51 recombinase directly inhibit DNA2 nuclease at stalled replication forks and FANCD2 acts as a novel RAD51 mediator in strand exchange to promote genome stability.

RAD51 bypasses the CMG helicase to promote replication fork reversal

Replication fork uncoupling causes nascent strand degradation and fork reversal.

Single Molecular Resolution to Monitor DNA Replication Fork Dynamics upon Stress by DNA Fiber Assay.

Two replication fork remodeling pathways generate nuclease substrates for distinct fork protection factors

Collaborators (4)

Binghui Shen

David Cortez

James Dewar

Masato Kanemaki

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