William Brackenbury

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Senior Lecturer in Biomedical Sciences

University of York

United Kingdom

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William Brackenbury is a Senior Lecturer in Biomedical Sciences at the University of York, UK. His research encompasses the role of sodium channels in cancer, particularly breast cancer, as well as cellular dynamics and phenotyping techniques. Recent publications include studies on sodium accumulation in malignancies and the impact of sodium channel-inhibiting drugs on cancer survival.

Recent Grants

Grant: Close

Digital Spatial Profiling in biomedical research

Open Date: 2019-01-01

Close Date: 2024-01-01

Grant: Close

An integrated biophysics approach towards realisation of a new class of membrane-active anticancer therapies

Open Date: 2018-09-30

Close Date: 2022-03-30

Grant: Close

Targeting ion channels to improve cancer immunotherapy

Open Date: 2018-01-01

Close Date: 2020-01-01

Grant: Close

Can we exploit breast cancer sodium for diagnostic and therapeutic benefit?

Open Date: 2018-01-01

Close Date: 2020-01-01

Grant: Close

Investigating the relationship between sodium transport inhibitor use and clinical outcomes in cancer patients

Open Date: 2018-01-01

Close Date: 2019-01-01

Articles (12)

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2025

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2024

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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UNITED KINGDOM

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Lecturer in Molecular Biophysics

University of York

UNITED KINGDOM

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William Brackenbury

Research Interests

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Recent Grants

Articles (12)

Chloroform release from ageing cells and Drosophila DJ-1β mutants

Worldwide Sodium Channel Conference, January 31st–February 2nd, 2024, Grindelwald, Switzerland

The CellPhe toolkit for cell phenotyping using time-lapse imaging and pattern recognition

Sodium channels and the ionic microenvironment of breast tumours

Sodium regulates PLC and IP3R‐mediated calcium signaling in invasive breast cancer cells

Sodium channel-inhibiting drugs and cancer-specific survival: a population-based study of electronic primary care data

Subcellular dynamics and functional activity of the cleaved intracellular domain of the Na+ channel β1 subunit

Sodium accumulation in breast cancer predicts malignancy and treatment response

Sampling and Analysis of Low-Molecular-Weight Volatile Metabolites in Cellular Headspace and Mouse Breath

Harnessing the Membrane Potential to Combat Cancer Progression

Volatile compounds in human breath: critical review and meta-analysis

Inhibition of the Na+/K+-ATPase by cardiac glycosides suppresses expression of the IDO1 immune checkpoint in cancer cells by reducing STAT1 activation

Collaborators (9)

Aneurin James Kennerley

Peter John O'Toole

Gareth John Owen Evans

Sean Sweeney

Theo Issitt

Martin Veysey

Julie Wilson

Kelly Redeker

Christoph George Baumann

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