Wim Van Hul

PI/full professor

University of Antwerp

Belgium

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Wim Van Hul is a full professor at the University of Antwerp, Belgium. His research focuses on metabolic dysfunction-related diseases, genetic contributions to obesity, and bone disorders, as evidenced by his recent publications. His work also explores epigenetic mechanisms and evolutionary genetics, particularly in relation to conditions such as Paget’s disease and steatotic liver disease.

Wim Van Hul

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Articles (18)

Gradual DNA methylation changes reveal transcription factors implicated in metabolic dysfunction-associated steatotic liver disease progression and epigenetic age acceleration

Loss of the ubiquitin-associated domain of sqstm1/p62 in zebrafish causes a phenotype resembling Paget’s disease of bone

A Case–Control Study Supports Genetic Contribution of the <i>PON</i> Gene Family in Obesity and Metabolic Dysfunction Associated Steatotic Liver Disease

A Mosaic Variant in CTNNB1/β-catenin as a Novel Cause for Osteopathia Striata With Cranial Sclerosis

Evolutionary and functional analyses of LRP5 in archaic and extant modern humans

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)

Genetic Screening of ZNF687 and PFN1 in a Paget’s Disease of Bone Cohort Indicates an Important Role for the Nuclear Localization Signal of ZNF687

Osteocytic Sclerostin Expression as an Indicator of Altered Bone Turnover

An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling

A recessive form of craniodiaphyseal dysplasia caused by a homozygous missense variant in SP7/Osterix

Rare Heterozygous PCSK1 Variants in Human Obesity: The Contribution of the p.Y181H Variant and a Literature Review

Identification of Compound Heterozygous Variants in LRP4 Demonstrates That a Pathogenic Variant outside the Third β-Propeller Domain Can Cause Sclerosteosis

A Panel-Based Sequencing Analysis of Patients with Paget’s Disease of Bone Suggests Enrichment of Rare Genetic Variation in regulators of NF-κB Signaling and Supports the Importance of the 7q33 Locus

Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome

DNA Methylation Profiling and Genomic Analysis in 20 Children with Short Stature Who Were Born Small for Gestational Age.

Delineation of a new fibrillino-2-pathy with evidence for a role of FBN2 in the pathogenesis of carpal tunnel syndrome.

A multi-omics approach expands the mutational spectrum of MAP2K1-related melorheostosis.

WNT Signaling and Bone: Lessons From Skeletal Dysplasias and Disorders.

Collaborators (14)

Guy Van Camp

Francis de Zegher

Erik Fransen

Clair Baldock

Steven Van Laere

Thorsten Schinke

Wim Vanden Berghe

sven Francque

Daniela Bertinetti

Mathias Haarhaus

jean-pierre devogelaer

Anja Verhulst

Geert Mortier

Stijn Verhulst

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