Ruud Toonen

University of Amsterdam

Netherlands

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Articles (22)

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Collaborators (16)

Hanna Lammertse

University of Amsterdam

NETHERLANDS

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José Antonio Martínez López

SPAIN

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Femke Feringa

University of Amsterdam

NETHERLANDS

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ka wan li

University of Amsterdam

NETHERLANDS

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Mieke M. van Haelst

NETHERLANDS

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Robert Bruce Russell

Professor

Ruprecht Karls Universität Heidelberg

GERMANY

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Alessandro Moro

University of Amsterdam

NETHERLANDS

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Ganna Balagura

University of Amsterdam

NETHERLANDS

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Claudia Bagni

Vice-Dean for Research and Innovation

University of Lausanne

SWITZERLAND

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Claudia Persoon

University of Amsterdam

NETHERLANDS

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Cordelia Imig

Københavns Universitet

DENMARK

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Frank Koopmans

University of Amsterdam

NETHERLANDS

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Sophie van der Sluis

University of Amsterdam

NETHERLANDS

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Jan van Weering

University of Amsterdam

NETHERLANDS

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John Jia En Chua

Assistant Professor

National University of Singapore (NUS)

SINGAPORE

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Matthijs Verhage

NETHERLANDS

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Ruud Toonen

Research Interests

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Articles (22)

RIM and MUNC13 membrane–binding domains are essential for neuropeptide secretion

Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis

Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis

Neuronal Network Inactivity Potentiates Neuropeptide Release from Mouse Cortical Neurons

KIF5A regulates axonal repair and time-dependent axonal transport of SFPQ granules and mitochondria in human motor neurons

Reduced Protein Stability of 11 Pathogenic Missense STXBP1/MUNC18-1 Variants and Improved Disease Prediction

Reduced synaptic depression in human neurons carrying homozygous disease-causing STXBP1 variant L446F

High-throughput assay for regulated secretion of neuropeptides in mouse and human neurons

Rabphilin-3A negatively regulates neuropeptide release, through its SNAP25 interaction

Power and optimal study design in iPSC-based brain disease modelling

Transcriptional diversity in specific synaptic gene sets discriminates cortical neuronal identity

Tomosyn affects dense core vesicle composition but not exocytosis in mammalian neurons

Mapping localization of 21 endogenous proteins in the Golgi apparatus of rodent neurons

Reduced MUNC18-1 Levels, Synaptic Proteome Changes, and Altered Network Activity in STXBP1-Related Disorder Patient Neurons

Maximal Fusion Capacity and Efficient Replenishment of the Dense Core Vesicle Pool in Hippocampal Neurons

Tomosyn affects dense core vesicle composition but not exocytosis in mammalian neurons

Dysregulation of Synaptic and Developmental Transcriptomic/Proteomic Profiles upon Depletion of MUNC18-1

Reduced dynamin-1 levels in neurons lacking MUNC18-1

Differential axonal trafficking of Neuropeptide Y-, LAMP1-, and RAB7-tagged organelles in vivo

Vti1a/b support distinct aspects of TGN and cis-/medial Golgi organization

Epilepsy Course and Developmental Trajectories in STXBP1 -DEE

Neuronal F-Box protein FBXO41 regulates synaptic transmission and hippocampal network maturation

Collaborators (16)

Hanna Lammertse

José Antonio Martínez López

Femke Feringa

ka wan li

Mieke M. van Haelst

Robert Bruce Russell

Alessandro Moro

Ganna Balagura

Claudia Bagni

Claudia Persoon

Cordelia Imig

Frank Koopmans

Sophie van der Sluis

Jan van Weering

John Jia En Chua

Matthijs Verhage

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