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Yanling Wang

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Associate Professor

Rush University Medical Center

United States

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Recent Grants

Grant: Open

Investigating the Effect of APOE Alleles on Neuro-Immunity of Human Brain Borders in Normal Aging and Alzheimer's Disease Using Single-Cell Multi-Omics and In Vitro Organoids

Open Date: 2022-09-01

Close Date: 2027-05-31

Grant: Open

Uncovering cell-type-specific driver genes of Alzheimer's Disease by pathology-indexing scRNA-seq, spatial transcriptomics, and CRISPR screens

Open Date: 2022-04-15

Close Date: 2027-03-31

Articles (20)

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2023

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University of Toronto

CANADA

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Yanling Wang

Research Interests

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Recent Grants

Articles (20)

Cortical Gray Matter Proteins Associated With Cerebral Amyloid Angiopathy in Community-Dwelling Older Adults

Brain 5-hydroxymethylcytosine alterations are associated with Alzheimer's disease neuropathology.

Structural variants linked to Alzheimer’s disease and other common age-related clinical and neuropathologic traits

Identifying motor resilience proteins associated with motor decline in older adults

Proteome-wide association studies using summary pQTL data of brain, CSF, and plasma identify 30 risk genes of Alzheimer’s disease dementia

A Transcriptomic Signature of Depressive Symptoms in Late Life

Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression

CHRNA5 links chandelier cells to severity of amyloid pathology in aging and Alzheimer’s disease

SR-TWAS: leveraging multiple reference panels to improve transcriptome-wide association study power by ensemble machine learning

Cellular communities reveal trajectories of brain ageing and Alzheimer's disease.

Genetic architecture of epigenetic cortical clock age in brain tissue from older individuals: alterations in <i>CD46</i> and other loci.

Proteins linking APOE ɛ4 with Alzheimer's disease.

Elevated protease-activated receptor 4 (PAR4) gene expression in Alzheimer's disease predicts cognitive decline.

Cell subtype-specific effects of genetic variation in the Alzheimer's disease brain.

Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults.

Associations of VGF with Neuropathologies and Cognitive Health in Older Adults.

Zooming into finer brain structures in vitro.

Multi-omic integration via similarity network fusion to detect molecular subtypes of ageing.

TREM2 gene expression associations with Alzheimer's disease neuropathology are region-specific: implications for cortical versus subcortical microglia.

Estrogen Receptor Genes, Cognitive Decline, and Alzheimer Disease.

Collaborators (7)

Aliza Wingo

Gillian Coughlan

Jingjing Yang

Timothy Hohman

Bing Yao

Sonal Agrawal

Aristotle Voineskos

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Yanling Wang

Research Interests

Explore related searches

Recent Grants

Articles (20)

Cortical Gray Matter Proteins Associated With Cerebral Amyloid Angiopathy in Community-Dwelling Older Adults

Brain 5-hydroxymethylcytosine alterations are associated with Alzheimer's disease neuropathology.

Structural variants linked to Alzheimer’s disease and other common age-related clinical and neuropathologic traits

Identifying motor resilience proteins associated with motor decline in older adults

Proteome-wide association studies using summary pQTL data of brain, CSF, and plasma identify 30 risk genes of Alzheimer’s disease dementia

A Transcriptomic Signature of Depressive Symptoms in Late Life

Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression

CHRNA5 links chandelier cells to severity of amyloid pathology in aging and Alzheimer’s disease

SR-TWAS: leveraging multiple reference panels to improve transcriptome-wide association study power by ensemble machine learning

Cellular communities reveal trajectories of brain ageing and Alzheimer's disease.

Genetic architecture of epigenetic cortical clock age in brain tissue from older individuals: alterations in &lt;i&gt;CD46&lt;/i&gt; and other loci.

Proteins linking APOE ɛ4 with Alzheimer's disease.

Elevated protease-activated receptor 4 (PAR4) gene expression in Alzheimer's disease predicts cognitive decline.

Cell subtype-specific effects of genetic variation in the Alzheimer's disease brain.

Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults.

Associations of VGF with Neuropathologies and Cognitive Health in Older Adults.

Zooming into finer brain structures in vitro.

Multi-omic integration via similarity network fusion to detect molecular subtypes of ageing.

TREM2 gene expression associations with Alzheimer's disease neuropathology are region-specific: implications for cortical versus subcortical microglia.

Estrogen Receptor Genes, Cognitive Decline, and Alzheimer Disease.

Collaborators (7)

Aliza Wingo

Gillian Coughlan

Jingjing Yang

Timothy Hohman

Bing Yao

Sonal Agrawal

Aristotle Voineskos

Make your next move.

Genetic architecture of epigenetic cortical clock age in brain tissue from older individuals: alterations in <i>CD46</i> and other loci.