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Yifat Merbl

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Weizmann Institute of Science

Israel

Research Interests

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Professors in Immunology

Recent Grants

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Harnessing proteasome heterogeneity for sensitization to immunotherapy

Open Date: 2021-06-01

Close Date: 2023-05-31

Articles (15)

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2026

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2022

Collaborators (16)

Igor Smirnov

Associate professor

Washington University in St. Louis

UNITED STATES

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Fengchao Yu

University of Michigan

UNITED STATES

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Dana Reichmann

Associate professor

Hebrew University of Jerusalem

ISRAEL

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Jotham Suez

Assistant Professor

Johns Hopkins University

UNITED STATES

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Silke Meiners

GERMANY

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Kevin Litchfield

University College London

UNITED KINGDOM

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Paula da Fonseca

Professor of Cryo-Electron Microscopy

University of Glasgow

UNITED KINGDOM

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Cesar de la Fuente‐Nunez

University of Pennsylvania

UNITED STATES

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Natalie Vokes

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Eeva-Liisa Eskelinen

University of Helsinki

FINLAND

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Merav Shmueli

Staff Scientist

Weizmann Institute of Science

ISRAEL

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Lisa Sharkey

University of Michigan

UNITED STATES

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Cheryl Lichti

Assistant Professor

Washington University

UNITED STATES

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Rafael Valdés-Mas

Junior Group Leader

Universidad de Navarra

SPAIN

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Christopher McGinnis

Assistant Professor

The Wistar Institute

UNITED STATES

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Phyllis Hanson

University of Michigan

UNITED STATES

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Yifat Merbl

Research Interests

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Recent Grants

Articles (15)

Insights on Future Directions in Cancer Research from the AACR Trailblazer Cancer Research Grant Awardees

Encrypted immunity mediated by peptides

Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease.

Translation dysregulation in cancer as a source for targetable antigens

Cdc48 plays a crucial role in redox homeostasis through dynamic reshaping of its interactome during early stationary phase

Dissection of the immune landscape in psoriatic arthritis defines immunoproteasome up-regulation in treatment resistance

Cell-autonomous innate immunity by proteasome-derived defence peptides

Engineered T cell therapy for central nervous system injury

Repurposing of glatiramer acetate to treat cardiac ischemia in rodent models

Rab7-dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis

Upregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration.

The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC.

Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation

Large-Scale Immunopeptidome Analysis Reveals Recurrent Posttranslational Splicing of Cancer- and Immune-Associated Genes

Post-translational modifications reshape the antigenic landscape of the MHC I immunopeptidome in tumors

Collaborators (16)

Igor Smirnov

Fengchao Yu

Dana Reichmann

Jotham Suez

Silke Meiners

Kevin Litchfield

Paula da Fonseca

Cesar de la Fuente‐Nunez

Natalie Vokes

Eeva-Liisa Eskelinen

Merav Shmueli

Lisa Sharkey

Cheryl Lichti

Rafael Valdés-Mas

Christopher McGinnis

Phyllis Hanson

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