Yuan Chang

Distinguished Professor

University of Pittsburgh

United States

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Dr. Yuan Chang is a Distinguished Professor at the University of Pittsburgh, USA. His research primarily focuses on polyomaviruses and herpesviruses, exploring mechanisms of viral replication, signaling pathways, and the role of circular RNAs in cancer. Recent publications include studies on Merkel cell polyomavirus and its interactions with human cellular factors, as well as the infectivity of SARS-CoV-2 in various human cell types.

Articles (9)

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2023

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2023

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2022

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2021

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2021

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2020

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2020

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2020

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2020

Collaborators (4)

Patrick Moore

UNITED STATES

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Hyun Jin Kwun

Assistant Professor

Penn State College of Medicine

UNITED STATES

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MASAHIRO SHUDA

Assistant Professor

University of Pittsburgh

UNITED STATES

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Donna Stolz

Associate Professor

University of Pittsburgh

UNITED STATES

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Yuan Chang

Research Interests

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Articles (9)

Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-dependent helicase activity

Membrane-bound Merkel cell polyomavirus middle T protein constitutively activates PLCγ1 signaling through Src-family kinases

Replication Kinetics for a Reporter Merkel Cell Polyomavirus

SARS‐CoV‐2 pseudovirus infectivity and expression of viral entry‐related factors ACE2, TMPRSS2, Kim‐1, and NRP‐1 in human cells from the respiratory, urinary, digestive, reproductive, and immune systems

Sirolimus and Other Mechanistic Target of Rapamycin Inhibitors Directly Activate Latent Pathogenic Human Polyomavirus Replication

Merkel Cell Polyomavirus Encodes Circular RNAs (circRNAs) Enabling a Dynamic circRNA/microRNA/mRNA Regulatory Network

Merkel Cell Polyomavirus Encodes Circular RNAs (circRNAs) Enabling a Dynamic circRNA/microRNA/mRNA Regulatory Network

Proteomic approach to discover human cancer viruses from formalin-fixed tissues

Kaposi’s Sarcoma-Associated Herpesvirus-Encoded circRNAs Are Expressed in Infected Tumor Tissues and Are Incorporated into Virions

Collaborators (4)

Patrick Moore

Hyun Jin Kwun

MASAHIRO SHUDA

Donna Stolz

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