Yuan He

Associate Professor

Northwestern University

United States

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About

Yuan He is an Associate Professor at Northwestern University in the United States. His research focuses on genome regulation, chromatin dynamics, and DNA repair mechanisms, as evidenced by his recent publications on ATP-dependent chromatin remodelers, histone modifications, and structural insights into non-homologous end joining. Additionally, he explores the structural basis of transcription initiation and enzyme complexes involved in these critical biological processes.

Articles (12)

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2021

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2021

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2020

Collaborators (4)

Susan Lees-Miller

Professor

University of Calgary

CANADA

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Amy C. Rosenzweig

Northwestern University

UNITED STATES

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Ishwar Radhakrishnan

Professor

Northwestern University

UNITED STATES

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Karl-Peter Hopfner

Professor

Ludwig-Maximilians-Universität München

GERMANY

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Yuan He

Research Interests

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About

Articles (12)

Energy-driven genome regulation by ATP-dependent chromatin remodellers

Structure and function of the apical PIKKs in double-strand break repair

Structure and mechanism in non-homologous end joining

Histone Acetylation and Deacetylation – Mechanistic Insights from Structural Biology

Structural basis of TFIIIC-dependent RNA polymerase III transcription initiation

Cryo-EM visualization of DNA-PKcs structural intermediates in NHEJ

Cryo-EM structure of the Saccharomyces cerevisiae Rpd3L histone deacetylase complex

How to fix DNA breaks: new insights into the mechanism of non-homologous end joining

Recovery of particulate methane monooxygenase structure and activity in a lipid bilayer

Structural basis of long-range to short-range synaptic transition in NHEJ

Structure of the human Mediator-bound transcription preinitiation complex

Structural Insights into the Evolutionarily Conserved BAF Chromatin Remodeling Complex

Collaborators (4)

Susan Lees-Miller

Amy C. Rosenzweig

Ishwar Radhakrishnan

Karl-Peter Hopfner

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