Yue Qu
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Recent Grants
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Medtronic External Research Program
Open Date: 2020-02-01
Close Date: 2021-01-01
Grant: Close
Understanding extracellular polymer substance (EPS) mediated fungal-bacterial mixed biofilm formation and optimizing current treatment strategies for device-related polymicrobial infections
Open Date: 2018-01-01
Close Date: 2021-12-01
Grant: Close
An On Demand Bactericidal Surface to Halt Medical Device Biofouling
Open Date: 2017-11-01
Close Date: 2020-11-01
Grant: Close
Surface modifications prevent driveline infection
Open Date: 2016-10-01
Close Date: 2017-07-01
Grant: Close
Develop surface coatings for medical devices that resist the attachment of organisms and establishment of biofilms, particularly antibiotic resistance biofilms
Open Date: 2015-01-01
Close Date:
Articles (11)
Biofilm formation is an important microbial strategy for fungal pathogens, such as Fusarium, Aspergillus, and Candida, to establish keratitis in patients wearing soft contact lenses. Despite the well-documented 2006 outbreak of Fusarium keratitis that eventually led to the withdrawal of the Bausch & Lomb multipurpose lens care solution ReNu with MoistureLoc (“MoistureLoc”) from the global market, contact lens care systems and solutions currently available on the market do not specifically target fungal biofilms. This is partially due to the lack of recognition and understanding of important roles that fungal biofilms play in contact lens associated fungal keratitis (CLAFK). This review aims to reemphasize the link between fungal biofilms and CLAFK, and deepen our comprehension of its importance in pathogenesis and persistence of this medical device-related infection.
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2023
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2021
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2021
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2021
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2021
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2021
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2020
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2020
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2020
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2020
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2020
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