Yuk Yee Leung

Research Assistant Professor

University of Pennsylvania

United States

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Dr. Yuk Yee Leung is a Research Assistant Professor at the University of Pennsylvania, United States. Her research focuses on genetic and genomic studies related to Alzheimer's disease and progressive supranuclear palsy, as evidenced by her recent publications that explore whole-genome sequencing, structural variant analysis, and the implications of glial activation. Dr. Leung is also involved in developing tools for genomic data analysis and resources for understanding genetic factors in neurodegenerative diseases.

Articles (16)

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2025

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2020

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2020

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2020

Collaborators (10)

Rebecca Baillie

Chief of Staff

UNITED STATES

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Wan-Ping Lee

Research Assistant Professor

University of Pennsylvania

UNITED STATES

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William Bush

Associate Professor

Case Western Reserve University

UNITED STATES

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Jeffrey Burns

UNITED STATES

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Timothy Chang

Assistant Professor

University of California, Los Angeles

UNITED STATES

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Alejandro Nato

Associate Professor

Marshall University

UNITED STATES

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Najaf Amin

Associate Professor

University of Oxford

UNITED KINGDOM

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Shahzad Ahmad

University of Oxford

UNITED KINGDOM

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Pavel Kuksa

Research Assistant Professor

University of Pennsylvania

UNITED STATES

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Otto Valladares

University of Pennsylvania

UNITED STATES

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Yuk Yee Leung

Research Interests

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About

Articles (16)

Alzheimer's Disease Sequencing Project release 4 whole genome sequencing dataset

Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes

NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's disease genetic and genomic knowledge

Human whole-exome genotype data for Alzheimer's disease.

Author Correction: Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes

Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy.

A comparative study of structural variant calling in WGS from Alzheimer's disease families.

LUSTR: a new customizable tool for calling genome-wide germline and somatic short tandem repeat variants.

hipFG: high-throughput harmonization and integration pipeline for functional genomics data

Scalable approaches for functional analyses of whole-genome sequencing non-coding variants

Omnibus and robust deconvolution scheme for bulk RNA sequencing data integrating multiple single-cell reference sets and prior biological knowledge

ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer's disease.

Circulating ethanolamine plasmalogen indices in Alzheimer's disease: Relation to diagnosis, cognition, and CSF tau

Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

HiPR: High-throughput probabilistic RNA structure inference

SparkINFERNO: A scalable high-throughput pipeline for inferring molecular mechanisms of non-coding genetic variants

Collaborators (10)

Rebecca Baillie

Wan-Ping Lee

William Bush

Jeffrey Burns

Timothy Chang

Alejandro Nato

Najaf Amin

Shahzad Ahmad

Pavel Kuksa

Otto Valladares

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