Zhongsheng You

Associate Professor

Washington University in Saint Louis School of Medicine

United States

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About

Zhongsheng You is an Associate Professor at Washington University in St Louis School of Medicine, USA. His research primarily focuses on genome stability, DNA damage response, and tumor biology, as reflected in his recent publications. Notable topics include the regulation of ATM signaling, the role of lactyl-CoA synthetase in tumor promotion, and the vulnerabilities of cancer cells harboring specific mutations.

Articles (7)

Year:

2025

Year:

2025

Year:

2024

Year:

2023

Year:

2023

Year:

2021

Year:

2020

Collaborators (1)

Shan Yan

Professor

University of North Carolina at Charlotte

UNITED STATES

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Zhongsheng You

Research Interests

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Articles (7)

Cytosolic DNA and intracellular Ca2+: Maintaining genome stability during replication stress

ACSS2: Tumor-promoting lactyl-CoA synthetase that drives histone lactylation

Distinct regulation of ATM signaling by DNA single-strand breaks and APE1

The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery

The ATM-E6AP-MASTL axis mediates DNA damage checkpoint recovery

Nonsense-Mediated RNA Decay Is a Unique Vulnerability of Cancer Cells Harboring <i>SF3B1</i> or <i>U2AF1</i> Mutations

Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer

Collaborators (1)

Shan Yan

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