Ziyuan Guo

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Assistant Professor of Pediatrics

Cincinnati Children's Hospital Medical Center

United States

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Dr. Ziyuan Guo is an Assistant Professor of Pediatrics at Cincinnati Children's Hospital Medical Center in the United States. His research focuses on various aspects of neuroscience and pediatric health, including fear extinction mechanisms, the role of lncRNA in social behavior, and the modeling of brain disorders using human cerebral organoids. Recent publications highlight his work on Alzheimer's disease, cancer metastasis, and advanced imaging techniques in brain research.

Recent Grants

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Investigating cellular mechanisms underlying NF1-associated cognitive impairments using iPSCs

Open Date: 2016-06-01

Close Date: 2018-06-01

Articles (12)

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2025

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2022

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Boston University

UNITED STATES

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Ziyuan Guo

Research Interests

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Contact this professor

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Recent Grants

Articles (12)

Cpeb1 remodels cell type-specific translational program to promote fear extinction

Postsynaptic lncRNA Sera/Pkm2 pathway orchestrates the transition from social competition to rank by remodeling the neural ensemble in mPFC

Utilizing human cerebral organoids to model breast cancer brain metastasis in culture.

Modeling blood-brain barrier formation and cerebral cavernous malformations in human PSC-derived organoids.

Senktide blocks aberrant RTN3 interactome to retard memory decline and tau pathology in social isolated Alzheimer's disease mice.

Recalibrating the Why and Whom of Animal Models in Parkinson Disease: A Clinician's Perspective.

The interaction of Synapsin 2a and Synaptogyrin-3 regulates fear extinction in mice.

A general design of pyridinium-based fluorescent probes for enhancing two-photon microscopy.

Tau pathology epigenetically remodels the neuron-glial cross-talk in Alzheimer’s disease

Ultralong-Term Super-Resolution Tracking of Lysosomes in Brain Organoids by Near-Infrared Noble Metal Nanoclusters

Pharmacological rescue in patient iPSC and mouse models with a rare DISC1 mutation

Development of Neuroregenerative Gene Therapy to Reverse Glial Scar Tissue Back to Neuron-Enriched Tissue

Collaborators (5)

Rui Chen

Yanbo Fan

Christopher Elles

Jiajie Diao

Hengye Man

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