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Florian Hollfelder

Top university

10 months ago

Marie Curie PhD Studentship in Functional Metagenomics, Biochemistry, and Chemistry at University of Cambridge University of Cambridge in United Kingdom

Degree Level

PhD

Field of study

Biochemistry

Funding

This is a fully funded Marie Curie PhD studentship as part of the Horizon Europe MetaExplore network. Funding covers stipend and research costs for three years, with additional training and collaboration opportunities across Europe. Tuition coverage is included. Specific stipend amounts are not mentioned.

Deadline

Expired

Country flag

Country

United Kingdom

University

University of Cambridge

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Keywords

Biochemistry
Molecular Biology
Chemistry
Environmental Science
Biology
Structural Biology
Green Chemistry
Circular Economy
Directed Evolution
Bioinformatics
Biocatalyst
Microfluidics

About this position

The University of Cambridge is offering a prestigious Marie Curie PhD Studentship as part of the MetaExplore network, focusing on functional metagenomics and the discovery of novel biocatalysts for a sustainable circular economy. The project, led by Professor Florian Hollfelder in the Department of Biochemistry, aims to harness environmental sources for new catalysts that can be applied in recycling, bioremediation, and green chemistry. Research will involve ultrahigh throughput screening of metagenomic libraries using microfluidic picoliter droplets, enabling experimental interrogation of enzyme libraries with over 10 million members per day. Candidate enzymes will be mechanistically investigated, structurally characterized, and improved through directed evolution.

This studentship provides a unique opportunity to work in an international research environment, collaborating with various EU and UK groups within the MetaExplore network. The training includes both experimental and computational work, with a wide range of skill development in molecular biology, chemical biology, assay development, enzyme kinetics, DNA library generation, structural biology, organic synthesis, high-throughput screening, mechanistic enzymology, bioinformatics, and microfluidic engineering.

Applicants should hold a first or upper second class degree in chemistry, biochemistry, or a related subject, followed by a PhD. Experience in relevant laboratory techniques and research areas is highly desirable. The position is fully funded for three years, with support for tuition and research costs, and offers excellent career development opportunities in advanced molecular and biochemical research.

To apply, candidates should submit a cover letter describing their research interests, a detailed CV including exam marks and practical experience, a list of publications, and the names and email addresses of at least two referees familiar with their research work. Applications are to be submitted online via the University of Cambridge recruitment system, quoting reference PH48176. The deadline for applications is 2 January 2026. For informal enquiries, contact Professor Florian Hollfelder at [email protected].

This opportunity is ideal for motivated, research-driven candidates seeking to advance their careers in functional metagenomics, biochemistry, and sustainable science within a world-class academic environment.

Funding details

This is a fully funded Marie Curie PhD studentship as part of the Horizon Europe MetaExplore network. Funding covers stipend and research costs for three years, with additional training and collaboration opportunities across Europe. Tuition coverage is included. Specific stipend amounts are not mentioned.

What's required

Applicants must have a first or upper second class degree in chemistry, biochemistry, or a closely related subject, followed by a PhD. Experience with molecular and chemical biology techniques is preferred. Specific skills in assay development, enzyme kinetics, DNA library generation, structural biology, organic synthesis, high-throughput screening, mechanistic enzymology, bioinformatics, and microfluidic engineering are advantageous. Applications should include a cover letter describing research interests, a detailed CV with exam marks and practical experience, a list of publications, and contact details for at least two referees familiar with the applicant's research.

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Professors

Professor at University of Cambridge

University Name
Country flag

United Kingdom

Research Interests

Biochemistry

Biochemical Engineering

Microfluidic

Biocatalysis

Biology