PhD Studentship: Allele-resolved genetics and epigenetics in type 2 diabetes University of Exeter in United Kingdom

[Home tuition fees plus a Doctoral Stipend for up to 4 years.] PhD Studentship at the University of Exeter in From Variants to Placental Function: Using Cell-free DNA to Dissect the Functional Genomics of Adverse Pregnancy Outcomes . This project explores how genetic variants influence placental biology and adverse pregnancy outcomes such as preeclampsia, foetal growth restriction, and pre-term delivery. The research uses cell-free DNA (cfDNA) from maternal blood as a minimally invasive way to i...

[Funding covers fees plus a stipend of £21,805 per annum for 2026/7.] PhD studentship at the University of Exeter on "One read, one cell: Decoding cell identity with long-read sequencing" . This project sits at the intersection of functional genomics, epigenomics, mathematics, and computer science. It aims to resolve cell-type-specific epigenetic profiles directly from long-read sequencing data, without the need to physically separate cells from complex tissues. Using methylation patterns from O...

[Home tuition fees and a Doctoral Stipend for up to 4 years.] This PhD studentship at the University of Exeter investigates how defects in the minor spliceosome can trigger a highly specific form of autoimmune diabetes. The project is built around an important biological puzzle: inherited changes in the minor spliceosome components RNU4ATAC and RNU6ATAC can cause monogenic autoimmune diabetes, yet the minor splicing machinery is used in every cell. The studentship aims to identify which U12-intr...

[Funding of fees plus a stipend of £21,805 per annum for 2026/7.] This is a fully funded PhD studentship at the University of Exeter focused on decoding cellular diversity in the human brain and functionally annotating neuronal subtypes across development and disease. The project addresses a major challenge in neuroscience: while single-cell RNA sequencing has revealed many excitatory and inhibitory neuronal subtypes, the regulatory mechanisms that establish and maintain these identities are sti...

[Full tuition fees plus a stipend of £21,805 per annum for 2026/7.] PhD studentship at the University of Exeter on developing a new variant effect predictor for multiple missense variants in the same protein molecule. This EPSRC-funded project tackles an important challenge in clinical genomics: most variant interpretation tools assess missense changes one at a time, even though many patients carry multiple variants in the same gene or protein. The project will develop and validate a new computa...