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University of East Anglia

PhD Studentship: Decoding the molecular switches that control fungal growth and infection University of East Anglia in United Kingdom

Degree Level

PhD

Field of study

Microbiology

Funding

Available

Deadline

Nov 30, 2026

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Country

United Kingdom

University

University of East Anglia

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Keywords

Microbiology
Biology
Structural Biology
Medical Science
Fungal Biology
Nmr Spectroscopy
Genomic
Antifungal Resistance
Bioinformatic
Metabolomic

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About this position

[4-year fully funded Norwich Research Park Biosciences Doctoral Training Partnership PhD studentship including payment of tuition fees, a stipend for living expenses (£21,805 for 2026/27), and a Research Training Support Grant of £5,000 per year.]

PhD Studentship at the University of East Anglia, based within the Norwich Research Park Biosciences Doctoral Training Programme (NRPDTP), investigating how unusual DNA and RNA structures called G-quadruplexes (G4s) regulate fungal growth and infection.

This project focuses on Aspergillus fumigatus, an important human fungal pathogen, and aims to test whether G4s act as molecular switches that control the metabolic changes required for spore germination, hyphal development, biofilm formation, and antifungal susceptibility. Fungal infections are a major global health challenge and are increasingly difficult to treat because of antifungal resistance.

The successful PhD student will receive multidisciplinary training in molecular microbiology, fungal genetics, genomics, bioinformatics, CRISPR-Cas9 genome editing, metabolomics, microscopy, structural biology, and NMR spectroscopy. Research activities include genome-wide mapping of G4 formation, engineering targeted mutants, analysing metabolic changes, and investigating fungal cell-wall remodelling and drug response.

The studentship is fully funded for 4 years and includes tuition fees, an annual stipend for living costs, and a Research Training Support Grant. The 2026/27 stipend rate is £21,805, with £5,000 per year additional training support. NRPDTP students also complete a three-month professional internship placement (PIPS) during the programme.

Applicants should normally hold or expect to obtain at least a 2:1 honours degree (or equivalent) in microbiology, molecular biology, biochemistry, biomedical sciences, or a closely related subject. An English language level equivalent to IELTS 6.5 overall with 6.0 in each component is required. The project is open to candidates from all backgrounds and the programme emphasizes inclusive and supportive research culture.

Application deadline: 30 November 2026. Shortlisted applicants will be interviewed on 2, 3, and 4 February 2027. Intended start date: 1 October 2027.

Funding details

Available

What's required

Applicants should have, or expect to obtain, at least a 2:1 honours degree (or equivalent) in microbiology, molecular biology, biochemistry, biomedical sciences, or a related discipline. English language requirement: IELTS 6.5 overall with 6.0 in each category (Faculty of Science equivalent).

How to apply

Apply through the University of East Anglia postgraduate research application portal. Use the bespoke NRPDTP Personal and Research statement templates required for this programme. Submit before 30 November 2026.

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