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University of Birmingham

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University of Birmingham PhD Studentship

PhD Studentship in Metagenomic Insights into Respiratory Microbiome Dynamics and Disease Severity University of Birmingham in United Kingdom

Degree Level

PhD

Field of study

Computer Science

Funding

Available

Deadline

Nov 23, 2026

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Country

United Kingdom

University

University of Birmingham

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Keywords

Computer Science
Biology
Medical Science
Pathogen Detection
Microbiome Research
Disease Classification
Bacteriophage
Bioinformatic
Respiratory Infection
ML

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About this position

The University of Birmingham is offering a PhD studentship in metagenomic insights into respiratory microbiome dynamics across the disease severity spectrum. Based in Birmingham, United Kingdom, the project investigates how bacterial, viral, and fungal communities change from respiratory symptoms presenting in emergency care to severe pneumonia requiring intensive care.

The research will use large-scale metagenomic sequencing data and advanced computational biology methods for microbial profiling, genome reconstruction, and analysis of respiratory microbial ecology. Particular emphasis will be placed on the virome, including bacteriophages and anelloviruses, and on phage–bacteria interactions associated with microbial imbalance, infection, and disease progression.

A major component will involve developing machine-learning models that integrate bacterial, viral, and ecological microbiome features for pathogen detection, disease-severity classification, and early identification of patients at risk of clinical deterioration. The project combines fundamental microbiology with translational clinical and public-health research, offering opportunities to collaborate with clinicians and microbiologists.

The supervisory team comprises Professor Nick Loman, Dr Meera Chand, and Dr Sofia Morfopoulou. Applicants should have a computational or bioinformatics background and an interest in metagenomics, respiratory infections, microbial ecology, virology, machine learning, or clinical data analysis. The stated deadline is 23 November 2026. Funding details are not provided in the source post.

Funding details

Available

What's required

Applicants require a computational or bioinformatics background. The project involves analysis of large-scale metagenomic sequencing data and offers exposure to clinical and public health research, collaboration with clinicians and microbiologists, and development of technical and translational skills. No specific degree, GPA, or language-test requirements are stated in the post.

How to apply

Review the full project details and submit an application through the jobs.ac.uk listing. Follow the application instructions provided on the linked vacancy page before 23 November 2026.

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