PhD Studentship: Rare variant functional genomics for better understanding, prevention and treatment of musculoskeletal disorders University of Exeter in United Kingdom

[Full tuition fees plus a stipend of £21,805 per annum for 2026/7.] PhD studentship at the University of Exeter on developing a new variant effect predictor for multiple missense variants in the same protein molecule. This EPSRC-funded project tackles an important challenge in clinical genomics: most variant interpretation tools assess missense changes one at a time, even though many patients carry multiple variants in the same gene or protein. The project will develop and validate a new computa...

[Home tuition fees plus a Doctoral Stipend for up to 4 years.] PhD Studentship at the University of Exeter in From Variants to Placental Function: Using Cell-free DNA to Dissect the Functional Genomics of Adverse Pregnancy Outcomes . This project explores how genetic variants influence placental biology and adverse pregnancy outcomes such as preeclampsia, foetal growth restriction, and pre-term delivery. The research uses cell-free DNA (cfDNA) from maternal blood as a minimally invasive way to i...

[Funding covers fees plus a stipend of £21,805 per annum for 2026/7.] PhD studentship at the University of Exeter on "One read, one cell: Decoding cell identity with long-read sequencing" . This project sits at the intersection of functional genomics, epigenomics, mathematics, and computer science. It aims to resolve cell-type-specific epigenetic profiles directly from long-read sequencing data, without the need to physically separate cells from complex tissues. Using methylation patterns from O...

[Funded studentship with fees covered and a stipend of £21,805 per annum for 2026/7.] University of Exeter PhD Studentship in Decoding the rules of human gene interaction networks using combinatorial functional genomics . This funded doctoral project sits at the interface of functional genomics, molecular genetics, imaging, bioinformatics, statistics and data science. It addresses a major challenge in human genetics: understanding how combinations of genes interact to shape cellular phenotypes a...

[Funding of fees plus a stipend of £21,805 per annum for 2026/7.] This is a fully funded PhD studentship at the University of Exeter focused on decoding cellular diversity in the human brain and functionally annotating neuronal subtypes across development and disease. The project addresses a major challenge in neuroscience: while single-cell RNA sequencing has revealed many excitatory and inhibitory neuronal subtypes, the regulatory mechanisms that establish and maintain these identities are sti...