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The University of Manchester

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FSE PhD President's Doctoral Scholarship

PhD Studentship on UTIs and the Menopause: Microbial Competition, Hormone Signalling and Microfluidic Biosensing The University of Manchester in United Kingdom

Degree Level

PhD

Field of study

Biomedical Engineering

Funding

The four-year studentship is open to Home (UK) and international applicants. It provides an annual stipend at the UKRI minimum rate, currently £21,805 per year, plus a £1,000 annual enhancement, and a research training support grant of up to £20,000 for the full four-year programme. The project is in competition for funding with other projects and is expected to start in September 2027.

Deadline

Dec 18, 2026

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Country

United Kingdom

University

The University of Manchester

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Keywords

Biomedical Engineering
Biology
Mathematics
Mathematical Modeling
Medical Science
Menopause
Hormone Signaling
Biosensor
Genomic
Lab-on-a-chip Technology
Microfluidic
Bioinformatic
Urinary Tract

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About this position

This four-year PhD project investigates why urinary tract infection prevalence increases substantially during menopause. It examines how menopause-associated hormonal changes affect the urinary tract environment and alter competition between bacterial species in the distinctive flow conditions of the bladder and urethra.

The project will explore how changes in hormone signalling may disrupt microbial communities and their interactions with the host. A central focus is microbial communication: how cells sense and respond to biochemical and mechanical signals from other microbial species and from the host environment, and how these signals influence gene expression.

The research uses an interdisciplinary combination of mathematical modelling, microfluidic lab-on-a-chip experiments with cells, bioinformatics and genomics. The project will also examine how microfluidic devices can be designed and deployed as sensors and disease emulators, connecting quantitative modelling with experimental biosensing approaches.

The work is based at The University of Manchester and is supervised by Dr Thompson, within a research environment combining microbial biology, host-environment interactions, mathematical modelling, genomics and biomedical engineering methods.

Funding details

The four-year studentship is open to Home (UK) and international applicants. It provides an annual stipend at the UKRI minimum rate, currently £21,805 per year, plus a £1,000 annual enhancement, and a research training support grant of up to £20,000 for the full four-year programme. The project is in competition for funding with other projects and is expected to start in September 2027.

What's required

Applicants must hold or be about to obtain a minimum upper second-class undergraduate honours degree, or equivalent, in applied mathematics, physics, engineering or biology. Research experience in mathematical modelling and/or biology is desirable. Applicants must submit the full project title and supervisor names, previous-study details, contact details for two referees, a supporting statement, CV, and transcripts of awarded and in-progress university qualifications. Applicants should contact the main supervisor before applying, and late or incomplete applications will not be considered.

How to apply

Contact Dr Thompson to discuss the project and suitability. Submit a formal online application, selecting the FSE PhD President’s Doctoral Scholarship programme, and upload the supporting statement, CV, transcripts, project and supervisor details, and two referees’ contact details.

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